Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 13/20 | 0.66 |
| ▸ | PPARG | P37231 | 10/20 | 0.66 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | PPARD | Q03181 | 5/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11738947 | 0.95 | PPARG (0.72) | PPARAPPARGMEN1KMT2ACYP2C19 | |
| SCHEMBL4036404 | 0.90 | PPARG (0.66) | PPARAPPARGMEN1KMT2ACYP2C19 | |
| SCHEMBL4036197 | 0.90 | PPARG (0.66) | PPARAPPARGMEN1KMT2ACYP2C19 | |
| SCHEMBL4033117 | 0.86 | PPARA (0.60) | PPARAPPARGMEN1KMT2ACYP2C19 | |
| SCHEMBL4035971 | 0.86 | MAP4K4 (0.53) | PPARAPPARGMEN1KMT2ACYP2C19 | |
| SCHEMBL4038642 | 0.83 | PPARA (0.54) | PPARAPPARGMEN1KMT2ACYP2C19 | |
| SCHEMBL4042833 | 0.82 | PPARA (0.73) | PPARAPPARGMEN1KMT2ACYP2C19 | |
| SCHEMBL3483913 | 0.82 | PPARA (0.62) | PPARAPPARGCYP1A2CYP3A4ALDH1A1 | |
| SCHEMBL9416379 | 0.81 | PPARA (0.65) | PPARAPPARGMEN1KMT2ACYP2C19 | |
| SCHEMBL4036545 | 0.80 | PPARG (0.60) | PPARAPPARGMEN1KMT2ACYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2049107-A2 | SUBSTITUTED IMIDAZOLONE DERIVATIVES, PREPARATION AND USES | Genfit (FR) | 2009-04-22 | — | — | EP | disclosed |
| WO-2008012470-A2 | SUBSTITUTED IMIDAZOLONE DERIVATIVES, PREPARATION AND USES | GENFIT (FR) | 2008-01-31 | — | — | WO | disclosed |
| WO-2008012470-A2 | SUBSTITUTED IMIDAZOLONE DERIVATIVES, PREPARATION AND USES | GENFIT (FR) | 2008-01-31 | — | — | WO | disclosed |