SCHEMBL4036351

SCHEMBL4036351

CC(=O)NC1CCN(c2ccc3nc(Nc4c(C)cccc4Cl)c4cncn4c3n2)C1

nearest known ligand 0.69

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
LCK P06239 20/20 0.69
SRC P12931 1/20 0.69

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4038687 0.90 LCK (0.64) LCKSRC
SCHEMBL4036248 0.90 LCK (0.64) LCKSRC
SCHEMBL4037424 0.87 LCK (0.75) LCKSRC
SCHEMBL4039733 0.87 LCK (0.75) LCKSRC
SCHEMBL4036346 0.86 LCK (0.67) LCKSRC
SCHEMBL4041102 0.86 LCK (0.68) LCKSRC
SCHEMBL4038195 0.86 LCK (0.75) LCKSRC
SCHEMBL4039788 0.86 LCK (0.75) LCKSRC
SCHEMBL4045378 0.85 LCK (0.72) LCKSRC
SCHEMBL4038851 0.85 LCK (0.69) LCKSRC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1066286-B1 HETEROCYCLO-SUBSTITUTED IMIDAZOPYRAZINE PROTEIN TYROSINE KINASE INHIBITORS BRISTOL MYERS SQUIBB CO (US) 2009-04-29 EP claimed
EP-1240210-B1 ULTRA-HIGH-SOLIDS ACRYLIC COATINGS LYONDELL CHEMICAL TECH LP (US) 2007-03-14 EP claimed
EP-1240210-A4 ULTRA-HIGH-SOLIDS ACRYLIC COATINGS ARCO CHEM TECH (US) 2005-03-30 EP claimed
EP-1240210-A1 ULTRA-HIGH-SOLIDS ACRYLIC COATINGS ARCO Chemical Technology, L.P. (US) 2002-09-18 EP claimed
US-6294607-B1 Ultra-high-solids acrylic coatings ARCO CHEMICAL TECHNOLOGY, L.P. 2001-09-25 US claimed
WO-2001018071-A1 ULTRA-HIGH-SOLIDS ACRYLIC COATINGS ARCO CHEMICAL TECHNOLOGY, L.P. (US) 2001-03-15 WO claimed
EP-1066286-B1 HETEROCYCLO-SUBSTITUTED IMIDAZOPYRAZINE PROTEIN TYROSINE KINASE INHIBITORS BRISTOL MYERS SQUIBB CO (US) 2009-04-29 EP disclosed
EP-2010239-A2 WATER RESISTANT FILM FORMING COMPOSITIONS INCORPORATING HYDROPHILIC ACTIVITIES Symyx Technologies, Inc. (US) 2009-01-07 EP disclosed
WO-2007123789-A2 WATER RESISTANT FILM FORMING COMPOSITIONS INCORPORATING HYDROPHILIC ACTIVITIES SYMYX TECHNOLOGIES, INC. (US) 2007-11-01 WO disclosed
US-20070238807-A1 Water resistant film forming compositions incorporating hydrophilic activities SYMYX SOLUTIONS, INC. 2007-10-11 US disclosed
US-5908907-A ADDITION-CONDENSATION BLOCK POLYMER RHONE-POULENC CHIMIE (FR) 1999-06-01 US disclosed
US-5852093-A Vulcanizable rubber composition, seal used in dynamic state, and sealing material NIPPON ZEON CO., LTD. (JP) 1998-12-22 US disclosed
EP-0795580-A1 VULCANIZABLE RUBBER COMPOSITION, SEAL TO BE USED IN DYNAMIC STATE, AND MATERIAL THEREFOR NIPPON ZEON CO., LTD. (JP) 1997-09-17 EP disclosed
EP-0209879-A2 Colloidal size hydrophobic polymers particulate having discrete particles of an organic material dispersed therein THE DOW CHEMICAL COMPANY (US) 1987-01-28 EP disclosed