SCHEMBL40367

SCHEMBL40367

[O]CC(Cl)Cl

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10719079 0.74
SCHEMBL180324 0.70
SCHEMBL21723187 0.70
SCHEMBL23899 0.70
SCHEMBL4354763 0.67
SCHEMBL1040277 0.67
SCHEMBL2561945 0.59
SCHEMBL19712850 0.59
SCHEMBL5421343 0.59
SCHEMBL1315740 0.59

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 465 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023246872-A1 HETEROCYCLIC COMPOUND AS TAAR1 LIGAND AGONIST 山东绿叶制药有限公司 2023-12-28 WO claimed
WO-2023237097-A1 19-NOR-C3,3-DISUBSTITUTED C21-AZACYCLO-SUBSTITUTED STEROID AND METHOD FOR USING SAME 山东绿叶制药有限公司 2023-12-14 WO claimed
WO-2023104178-A1 PROTEIN KINASE INHIBITOR, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF 山东绿叶制药有限公司 2023-06-15 WO claimed
WO-2023072284-A1 GONADOTROPIN-RELEASING HORMONE ANTAGONIST, AND PREPARATION METHOD THEREFOR AND USE THEREOF 山东绿叶制药有限公司 2023-05-04 WO claimed
EP-0234104-B1 NOVEL PYRIDINYLPYRIMIDINE DERIVATIVES, METHOD FOR PRODUCTION THEREOF AND A PLANT DISEASE PROTECTANT CONTAINING THEM AS THE ACTIVE INGREDIENT SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1990-10-24 EP claimed
US-4752608-A Fungicidal pyridinylpyrimidine derivatives SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1988-06-21 US claimed
EP-0234104-A2 Novel pyridinylpyrimidine derivatives, method for production thereof and a plant disease protectant containing them as the active ingredient SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1987-09-02 EP claimed
US-4483919-A 1-PHENYL-2-SUBSTITUTED-3-OXO-PYRAZOLIDINE COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1984-11-20 US claimed
EP-4382100-A1 N-ACYLHYDRAZONE COMPOUNDS CAPABLE OF INHIBITING NAV1.7 AND/OR NAV1.8, PROCESSES FOR THE PREPARATION THEREOF, COMPOSITIONS, USES, METHODS FOR TREATMENT USING SAME, AND KITS Eurofarma Laboratórios S.A. (BR) 2024-06-12 EP disclosed
EP-4382101-A1 N-ACYLHYDRAZONE COMPOUNDS CAPABLE OF INHIBITING NAV1.7 AND/OR NAV1.8, PROCESSES FOR THE PREPARATION THEREOF, COMPOSITIONS, USES, METHODS FOR TREATMENT USING SAME, AND KITS Eurofarma Laboratórios S.A. (BR) 2024-06-12 EP disclosed
EP-4375286-A1 OXASPIRO DERIVATIVE, AND PREPARATION METHOD THEREFOR AND USE THEREOF Shujing Biopharma Co., Ltd (CN) 2024-05-29 EP disclosed
US-11993578-B2 Pyrazole-3-carboxylic acid amide derivative and pest control agent KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 2024-05-28 US disclosed
EP-4371979-A1 FORMAMIDE DERIVATIVE AND AGRICULTURAL OR HORTICULTURAL PLANT DISEASE CONTROL AGENT Kumiai Chemical Industry Co., Ltd. (JP) 2024-05-22 EP disclosed
US-11964957-B2 Pyrazole derivative and harmful organism-controlling agent KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 2024-04-23 US disclosed
EP-0234104-A2 Novel pyridinylpyrimidine derivatives, method for production thereof and a plant disease protectant containing them as the active ingredient SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1987-09-02 EP disclosed
US-4663469-A 4-hydroxy-l-threoninamides HOFFMAN-LA ROCHE INC. (US) 1987-05-05 US disclosed
US-4502994-A Enantiomeric synthesis of 3-amino-4-carbamoyloxymethyl-2-azetidonone-1-sulfate HOFFMANN-LA ROCHE INC. (US) 1985-03-05 US disclosed
US-4483919-A 1-PHENYL-2-SUBSTITUTED-3-OXO-PYRAZOLIDINE COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1984-11-20 US disclosed
EP-0111326-A1 Process for the manufacture of chiral azetidinones F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) 1984-06-20 EP disclosed
US-4365042-A Compositions of polyphenylene oxides with EPDM-silicone rubber GENERAL ELECTRIC COMPANY (US) 1982-12-21 US disclosed