⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2561945 | 0.71 | — | — | |
| SCHEMBL875090 | 0.69 | — | — | |
| SCHEMBL40367 | 0.67 | — | — | |
| SCHEMBL29768538 | 0.67 | — | — | |
| SCHEMBL1722024 | 0.65 | — | — | |
| SCHEMBL2566012 | 0.64 | — | — | |
| SCHEMBL2566450 | 0.64 | — | — | |
| SCHEMBL1983132 | 0.63 | — | — | |
| SCHEMBL28254447 | 0.63 | — | — | |
| SCHEMBL31296054 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0544819-A4 | INDOLE DERIVATIVES WHICH INHIBIT LEUKOTRIENE BIOSYNTHESIS | — | 1993-10-20 | — | — | EP | claimed |
| EP-0544819-A1 | INDOLE DERIVATIVES WHICH INHIBIT LEUKOTRIENE BIOSYNTHESIS. | ABBOTT LAB (US) | 1993-06-09 | — | — | EP | claimed |
| EP-4382101-A1 | N-ACYLHYDRAZONE COMPOUNDS CAPABLE OF INHIBITING NAV1.7 AND/OR NAV1.8, PROCESSES FOR THE PREPARATION THEREOF, COMPOSITIONS, USES, METHODS FOR TREATMENT USING SAME, AND KITS | Eurofarma Laboratórios S.A. (BR) | 2024-06-12 | — | — | EP | disclosed |
| EP-4382100-A1 | N-ACYLHYDRAZONE COMPOUNDS CAPABLE OF INHIBITING NAV1.7 AND/OR NAV1.8, PROCESSES FOR THE PREPARATION THEREOF, COMPOSITIONS, USES, METHODS FOR TREATMENT USING SAME, AND KITS | Eurofarma Laboratórios S.A. (BR) | 2024-06-12 | — | — | EP | disclosed |
| WO-2023010192-A1 | N-ACYLHYDRAZONE COMPOUNDS CAPABLE OF INHIBITING NAV1.7 AND/OR NAV1.8, PROCESSES FOR THE PREPARATION THEREOF, COMPOSITIONS, USES, METHODS FOR TREATMENT USING SAME, AND KITS | EUROFARMA LABORATÓRIOS S.A. (BR) | 2023-02-09 | — | — | WO | disclosed |
| CN-109311842-B | Herbicidal uracils | 巴斯夫欧洲公司 | 2022-03-25 | — | — | CN | disclosed |
| CN-111315738-B | Inhibitors of glutaminyl cyclase | 维沃永治疗股份公司 | 2021-08-03 | — | — | CN | disclosed |
| US-20200223825-A1 | INHIBITORS OF GLUTAMINYL CYCLASE | VIVORYON THERAPEUTICS N.V (DE) | 2020-07-16 | — | — | US | disclosed |
| CN-111315738-A | Inhibitors of glutaminyl cyclase | 维沃永治疗股份公司 | 2020-06-19 | — | — | CN | disclosed |
| EP-3461819-B1 | INHIBITORS OF GLUTAMINYL CYCLASE | PROBIODRUG AG (DE) | 2020-05-27 | — | — | EP | disclosed |
| WO-2019063414-A1 | INHIBITORS OF GLUTAMINYL CYCLASE | PROBIODRUG AG (DE) | 2019-04-04 | — | — | WO | disclosed |
| EP-1322661-A1 | TRITERPENES HAVING FUNGICIDAL ACTIVITY AGAINST YEAST | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2003-07-02 | — | — | EP | disclosed |
| US-20020128210-A1 | Triterpenes having human antifungal and antiyeast activity | REGENTS OF THE UNIVERSITY OF MINNESOTA | 2002-09-12 | — | — | US | disclosed |
| US-20020119935-A1 | Triterpenes having antibacterial activity | REGENTS OF THE UNIVERSITY OF MINNESOTA | 2002-08-29 | — | — | US | disclosed |
| WO-2002026762-A1 | TRITERPENES HAVING ANTIBACTERIAL ACTIVITY | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2002-04-04 | — | — | WO | disclosed |
| WO-2002026761-A1 | TRITERPENES HAVING FUNGICIDAL ACTIVITY AGAINST YEAST | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2002-04-04 | — | — | WO | disclosed |
| EP-0332387-B1 | Triazole derivatives, their preparation and their use as fungicides | SANKYO CO (JP) | 1993-11-24 | — | — | EP | disclosed |
| EP-0544819-A4 | INDOLE DERIVATIVES WHICH INHIBIT LEUKOTRIENE BIOSYNTHESIS | — | 1993-10-20 | — | — | EP | disclosed |
| EP-0544819-A1 | INDOLE DERIVATIVES WHICH INHIBIT LEUKOTRIENE BIOSYNTHESIS. | ABBOTT LAB (US) | 1993-06-09 | — | — | EP | disclosed |
| EP-0332387-A1 | Triazole derivatives, their preparation and their use as fungicides | Sankyo Company Limited (JP) | 1989-09-13 | — | — | EP | disclosed |