SCHEMBL40368

SCHEMBL40368

c1ccc(C2c3ccccc3Oc3ccccc32)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C9 P11712 1/20 0.55
MAOA P21397 1/20 0.54
MAOB P27338 1/20 0.54
LMNA P02545 4/20 0.53
MEN1 O00255 4/20 0.53
KMT2A Q03164 4/20 0.53
MAPT P10636 3/20 0.53
ATM Q13315 2/20 0.50
NISCH Q9Y2I1 1/20 0.46
GAA P10253 1/20 0.44
HDAC3 O15379 1/20 0.42
HDAC4 P56524 1/20 0.42
HDAC1 Q13547 1/20 0.42
HDAC7 Q8WUI4 1/20 0.42
HDAC2 Q92769 1/20 0.42
HDAC10 Q969S8 1/20 0.42
HDAC11 Q96DB2 1/20 0.42
HDAC8 Q9BY41 1/20 0.42
HDAC6 Q9UBN7 1/20 0.42
HDAC9 Q9UKV0 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6241456 0.84 CYP2C9 (0.42) CYP2C9MAOAMAOBLMNAMEN1
SCHEMBL24402162 0.84 GAA (0.56) CYP2C9MAOAMAOBLMNAMEN1
SCHEMBL501810 0.83 GAA (0.65) CYP2C9MAOAMAOBLMNAMEN1
SCHEMBL7058082 0.83 FFAR4 (0.49) CYP2C9MAOAMAOBLMNAMEN1
SCHEMBL9698291 0.81 MAOA (0.45) CYP2C9MAOAMAOBLMNAMEN1
Phosphine SCHEMBL23295992 0.81 GAA (0.63) CYP2C9MAOAMAOBLMNAMEN1
SCHEMBL11781441 0.81 CYP2C9 (0.44) CYP2C9MAOAMAOBLMNAMEN1
SCHEMBL2098554 0.80 MAOA (0.44) CYP2C9MAOAMAOBLMNAMEN1
SCHEMBL31085591 0.80 CYP1A2 (0.45) CYP2C9MAOAMAOBLMNAMEN1
SCHEMBL22615 0.80 CYP2C9 (0.42) CYP2C9MAOAMAOBLMNAMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 6654 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12616921-B2 Process for the deprotection of oligonucleotides HOFFMANN-LA ROCHE INC. (US) 2026-05-05 US claimed
CN-119331036-A Tri-cluster galactose compound, conjugate, preparation method and application thereof 广州市锐博生物科技有限公司 2025-01-21 CN claimed
US-12043642-B2 Process for the purification of oligonucleotides GENENTECH, INC. (US) 2024-07-23 US claimed
US-20240239833-A1 ALKOXYPHENYL DERIVATIVES, PROTECTED NUCLEOSIDES AND PROTECTED NUCLEOTIDES, METHOD FOR PRODUCING OLIGONUCLEOTIDES, AND METHOD FOR REMOVING SUBSTITUENTS FUJIMOTO CHEMICALS CO., LTD., (JP) 2024-07-18 US claimed
EP-4396193-A1 FUNCTIONALIZED N-ACETYLGALACTOSAMINE ANALOGS Hongene Biotech Corporation (US) 2024-07-10 EP claimed
CN-118317970-A Synthesis of 2' acetyl-ester protected nucleosides 兆维生物科技公司 2024-07-09 CN claimed
WO-2024137756-A1 COMPOUNDS AND METHODS FOR LIQUID PHASE OLIGONUCLEOTIDE SYNTHESIS HONGENE BIOTECH CORPORATION (US) 2024-06-27 WO claimed
EP-4380624-A1 MULTIVALENT LIGAND CLUSTERS WITH DIAMINE SCAFFOLD FOR TARGETED DELIVERY OF THERAPEUTIC AGENTS Shanghai Argo Biopharmaceutical Co., Ltd. (CN) 2024-06-12 EP claimed
WO-2024118503-A1 FUNCTIONALIZED N-ACETYLGALACTOSAMINE ANALOGS HONGENE BIOTECH CORPORATION (US) 2024-06-06 WO claimed
US-11993626-B2 Functionalized N-acetylgalactosamine analogs HONGENE BIOTECH CORPORATION (US) 2024-05-28 US claimed
WO-1992006134-A1 CROSSLINKING POLYMERS WITH COMPOUNDS CONTAINING XANTHENE GROUPS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1992-04-16 WO claimed
US-5102808-A Method and test kit for analysis of histamine receptor sites of mammalian cells BOARD OF GOVERNORS OF WAYNE STATE UNIVERSITY (US) 1992-04-07 US claimed
EP-0241363-B1 NUCLEOSIDE DERIVATIVES AND THEIR USE IN THE SYNTHESIS OF OLIGONUCLEOTIDES COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) 1991-09-25 EP claimed
EP-0424819-A1 Reversible modification of biological compounds for detection, separation and purification thereof MILLIPORE CORPORATION (US) 1991-05-02 EP claimed
US-4849513-A Deoxyribonucleoside phosphoramidites in which an aliphatic amino group is attached to the sugar ring and their use for the preparation of oligonucleotides containing aliphatic amino groups CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 1989-07-18 US claimed
US-4830961-A Method and test kit for analysis of histamine receptor sites of mammalian cells BOARD OF GOVERNORS OF WAYNE STATE UNIVERSITY (US) 1989-05-16 US claimed
EP-0270651-A4 NOVEL DEOXYRIBONUCLEOSIDE PHOSPHORAMIDITES AND THEIR USE FOR THE PREPARATION OF OLIGONUCLEOTIDES. CALIFORNIA INST OF TECHN (US) 1989-03-29 EP claimed
EP-0270651-A1 NOVEL DEOXYRIBONUCLEOSIDE PHOSPHORAMIDITES AND THEIR USE FOR THE PREPARATION OF OLIGONUCLEOTIDES. CALIFORNIA INST OF TECHN (US) 1988-06-15 EP claimed
WO-1988000201-A1 NOVEL DEOXYRIBONUCLEOSIDE PHOSPHORAMIDITES AND THEIR USE FOR THE PREPARATION OF OLIGONUCLEOTIDES CALIFORNIA INSTITUTE OF TECHNOLOGY, INC. (US) 1988-01-14 WO claimed
US-3966638-A POLYMERIZATION CATALYST HARGIS IVAN GLEN 1976-06-29 US claimed