Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonium Lupinoate SCHEMBL27185103 | 0.98 | TDP1 (0.46) | TDP1TSHRHTTMEN1KMT2A | |
| Ammonium Lupinoate SCHEMBL29108995 | 0.98 | TDP1 (0.46) | TDP1TSHRHTTMEN1KMT2A | |
| Ammonium Lupinoate SCHEMBL29108993 | 0.98 | TDP1 (0.46) | TDP1TSHRHTTMEN1KMT2A | |
| SCHEMBL10340118 | 0.98 | TDP1 (0.44) | TDP1MEN1KMT2ASIGMAR1OPRM1 | |
| SCHEMBL10340120 | 0.98 | TDP1 (0.44) | TDP1MEN1KMT2ASIGMAR1OPRM1 | |
| SCHEMBL10340119 | 0.98 | TDP1 (0.44) | TDP1MEN1KMT2ASIGMAR1OPRM1 | |
| SCHEMBL6262157 | 0.89 | MEN1 (0.40) | TDP1MEN1KMT2A | |
| SCHEMBL14061760 | 0.89 | MEN1 (0.40) | TDP1MEN1KMT2A | |
| SCHEMBL6393607 | 0.86 | TDP1 (0.46) | TDP1TSHRHTTMEN1KMT2A | |
| SCHEMBL15714772 | 0.82 | KMT2A (0.43) | TSHRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-9272853-A | — | — | None | — | — | JP | disclosed |
| CN-105431432-A | Quinine compounds, and optical isomers, preparation method and medical use thereof | BEIJING JIASHI LIANBO PHARM SCI & TECH CO LTD | 2016-03-23 | — | — | CN | disclosed |
| US-8822039-B2 | Charge-transporting varnish and organic electro-luminescent devices made by using the same | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2014-09-02 | — | — | US | disclosed |
| CN-102740838-A | Carvedilol controlled release formulation | TSH BIOPHARM CO LTD | 2012-10-17 | — | — | CN | disclosed |
| EP-1275679-B1 | Polyamide acid and polyimide, and optical material | NIPPON CATALYTIC CHEM IND (JP) | 2009-04-29 | — | — | EP | disclosed |
| WO-2009029375-A1 | NOVEL INHIBITORS OF POLY(ADP-RIBOSE)POLYMERASE (PARP) | LEAD THERAPEUTICS, INC. (US) | 2009-03-05 | — | — | WO | disclosed |
| US-20090062268-A1 | NOVEL INHIBITORS OF POLY(ADP-RIBOSE)POLYMERASE (PARP) | LEAD THERAPEUTICS, INC. (US) | 2009-03-05 | — | — | US | disclosed |
| US-20070187672-A1 | Charge-transporting varnish and organic electro-luminescent devices made by using the same | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2007-08-16 | — | — | US | disclosed |
| EP-1728827-A1 | CHARGE-TRANSPORTING VARNISH AND ORGANIC ELECTRO- LUMINESCENT DEVICES MADE BY USING THE SAME | Nissan Chemical Industries, Ltd. (JP) | 2006-12-06 | — | — | EP | disclosed |
| CN-1777415-A | Medicinal composition containing edible acid or its acid salt and its use | XIAO XINGREN (CN) | 2006-05-24 | — | — | CN | disclosed |
| US-20030050407-A1 | Polyamide acid and polyimide, and optical material | NIPPON SHOKUBAI CO., LTD (JP) | 2003-03-13 | — | — | US | disclosed |
| EP-1275679-A1 | Polyamide acid and polyimide, and optical material | Nippon Shokubai Co., Ltd. (JP) | 2003-01-15 | — | — | EP | disclosed |
| US-6207364-B1 | BOTH SURFACES WHICH ARE COVERED WITH A RESIN THERMAL SHRINKAGE RATIO OF NOT MORE THAN 0.02% AT 150 DEGREES C. FOR 30 MINUTES, AND AN IMAGE FORMING LAYER COMPRISING AN ORGANIC SILVER. | KONICA CORPORATION (JP) | 2001-03-27 | — | — | US | disclosed |
| EP-0952482-A1 | Thermally developable material | KONICA CORPORATION (JP) | 1999-10-27 | — | — | EP | disclosed |
| JP-H09272853-A | FILM-TYPE ADHESIVE AGENT IMPROVED IN HEAT RESISTANCE, AND ITS PRODUCTION | SUMITOMO BAKELITE CO LTD | 1997-10-21 | — | — | JP | disclosed |
| EP-0710237-A1 | QUINOLIZIDINES WITH CALCIUM CHANNEL ANTAGONISTIC ACTIVITY | SMITHKLINE BEECHAM PLC (GB) | 1996-05-08 | — | — | EP | disclosed |
| WO-1995003302-A1 | QUINOLIZIDINES WITH CALCIUM CHANNEL ANTAGONISTIC ACTIVITY | SMITHKLINE BEECHAM PLC (GB) | 1995-02-02 | — | — | WO | disclosed |
| EP-0304136-B1 | Novel photosensitive composition | ASAHI CHEMICAL IND (JP) | 1994-06-29 | — | — | EP | disclosed |
| US-5019482-A | Polymer/oxime ester/coumarin compound photosensitive composition | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1991-05-28 | — | — | US | disclosed |
| EP-0304136-A2 | Novel photosensitive composition | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1989-02-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090062268-A1 | NOVEL INHIBITORS OF POLY(ADP-RIBOSE)POLYMERASE (PARP) | PARP1, PARP11, PARP2 | TDP1 47/4885TSHR 4074/4885HTT 1555/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.