Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 2/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | DHFR | P00374 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.37 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1925902 | 0.86 | CNR2 (0.50) | CNR2PTGS2MAPTDHFRGFER | |
| SCHEMBL1927657 | 0.84 | CNR2 (0.48) | CNR2PTGS2MAPTDHFRGFER | |
| SCHEMBL197161 | 0.83 | CNR2 (0.71) | CNR2PTGS2PTGS1CNR1 | |
| Hydrochloric Acid SCHEMBL1927665 | 0.83 | CNR2 (0.47) | CNR2PTGS2MAPTDHFRGFER | |
| Hydrochloric Acid SCHEMBL4576062 | 0.82 | CNR2 (0.69) | CNR2PTGS2PTGS1CNR1 | |
| SCHEMBL1927463 | 0.78 | CNR2 (0.46) | CNR2MAPTMEN1RAB9AL3MBTL1 | |
| SCHEMBL1927593 | 0.75 | CNR2 (0.54) | CNR2PTGS2MAPTGFERPTGS1 | |
| SCHEMBL5097779 | 0.72 | CNR2 (0.67) | CNR2PTGS2PTGS1CNR1LOXL2 | |
| SCHEMBL1926401 | 0.72 | CNR2 (0.67) | CNR2PTGS2MAPTPTGS1RAB9A | |
| SCHEMBL8362957 | 0.70 | ATP4A (0.62) | MAPTMEN1RAB9ACYP1A1CYP1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1379514-B1 | 5-MEMBERED HETEROCYCLES, PREPARATION AND APPLICATION THEREOF AS MEDICAMENTS | IPSEN PHARMA (FR) | 2009-07-15 | — | — | EP | claimed |