Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.52 |
| ▸ | RXRA | P19793 | 2/20 | 0.51 |
| ▸ | RXRB | P28702 | 2/20 | 0.51 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.49 |
| ▸ | DGAT1 | O75907 | 6/20 | 0.47 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | SLC13A5 | Q86YT5 | 2/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.45 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3485054 | 0.86 | FFAR4 (0.47) | CYP2C9FFAR4RXRARXRBGGPS1 | |
| SCHEMBL8264194 | 0.86 | DGAT1 (0.53) | CYP2C9FFAR4DGAT1MAP4K4MAPT | |
| SCHEMBL4033084 | 0.85 | SLC13A5 (0.48) | RXRARXRBGGPS1DGAT1MAP4K4 | |
| SCHEMBL4035381 | 0.85 | PPARA (0.60) | CYP2C9FFAR4RXRARXRBCYP1A2 | |
| SCHEMBL13948414 | 0.80 | CYP2C9 (0.61) | CYP2C9DGAT1MAP4K4CYP1A2 | |
| SCHEMBL4033955 | 0.78 | MAP4K4 (0.54) | CYP2C9FFAR4RXRARXRBMAP4K4 | |
| SCHEMBL20777094 | 0.78 | FFAR4 (0.45) | FFAR4RXRARXRBGGPS1CYP1A2 | |
| SCHEMBL5724626 | 0.77 | PPARA (0.58) | CYP2C9DGAT1MAP4K4 | |
| SCHEMBL21749010 | 0.77 | SSTR4 (0.56) | CYP2C9DGAT1MAP4K4MRGPRX4 | |
| SCHEMBL30783154 | 0.77 | SSTR4 (0.56) | CYP2C9DGAT1MAP4K4MRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2049107-A2 | SUBSTITUTED IMIDAZOLONE DERIVATIVES, PREPARATION AND USES | Genfit (FR) | 2009-04-22 | — | — | EP | disclosed |
| WO-2008012470-A2 | SUBSTITUTED IMIDAZOLONE DERIVATIVES, PREPARATION AND USES | GENFIT (FR) | 2008-01-31 | — | — | WO | disclosed |