Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.35 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.35 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4357340 | 1.00 | ALDH1A1 (0.47) | ALDH1A1MAPTL3MBTL1KDM4EMEN1 | |
| SCHEMBL3942258 | 0.94 | ALDH1A1 (0.45) | ALDH1A1MAPTL3MBTL1KDM4EMEN1 | |
| SCHEMBL3950925 | 0.89 | MAPT (0.51) | ALDH1A1MAPTL3MBTL1KDM4EMEN1 | |
| SCHEMBL4211554 | 0.88 | MAPT (0.50) | ALDH1A1MAPTL3MBTL1KDM4EMEN1 | |
| SCHEMBL3946900 | 0.87 | ALDH1A1 (0.49) | ALDH1A1MAPTL3MBTL1KDM4EMEN1 | |
| SCHEMBL3941334 | 0.86 | MAPT (0.49) | ALDH1A1MAPTL3MBTL1KDM4EMEN1 | |
| SCHEMBL3950155 | 0.85 | ALDH1A1 (0.46) | ALDH1A1MAPTL3MBTL1KDM4EMEN1 | |
| SCHEMBL3944219 | 0.82 | ALDH1A1 (0.44) | ALDH1A1MAPTL3MBTL1KDM4EMEN1 | |
| SCHEMBL4030827 | 0.82 | ALDH1A1 (0.44) | ALDH1A1MAPTL3MBTL1KDM4EMEN1 | |
| SCHEMBL4357338 | 0.82 | ALDH1A1 (0.57) | ALDH1A1MAPTL3MBTL1KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009019508-A1 | CALCIUM ION CHANNEL MODULATORS & USES THEREOF | LECTUS THERAPEUTICS LIMITED (GB) | 2009-02-12 | — | — | WO | disclosed |