Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4837889 | 0.98 | ALDH1A1 (0.54) | ALDH1A1KMT2ALMNAL3MBTL1MEN1 | |
| Hydrochloric Acid SCHEMBL514985 | 0.91 | KAT2B (0.57) | ALDH1A1KMT2ALMNAL3MBTL1MEN1 | |
| SCHEMBL10619771 | 0.90 | ALDH1A1 (0.62) | ALDH1A1KMT2ALMNAL3MBTL1MEN1 | |
| SCHEMBL5807817 | 0.86 | ALDH1A1 (0.56) | ALDH1A1KMT2ALMNAL3MBTL1MEN1 | |
| SCHEMBL1342619 | 0.86 | ALDH1A1 (0.57) | ALDH1A1KMT2ALMNAL3MBTL1MEN1 | |
| SCHEMBL12629238 | 0.84 | ALDH1A1 (0.55) | ALDH1A1KMT2ALMNAL3MBTL1MEN1 | |
| SCHEMBL5807820 | 0.84 | ALDH1A1 (0.57) | ALDH1A1KMT2ALMNAL3MBTL1MEN1 | |
| SCHEMBL1585310 | 0.84 | ALDH1A1 (0.57) | ALDH1A1KMT2ALMNAL3MBTL1MEN1 | |
| SCHEMBL14033156 | 0.84 | ALDH1A1 (0.72) | ALDH1A1LMNAKDM4EPKMS1PR4 | |
| SCHEMBL1339942 | 0.84 | ALDH1A1 (0.57) | ALDH1A1KMT2ALMNAL3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1885695-B1 | INDOLINE COMPOUNDS | FOURNIER LAB SA (FR) | 2009-02-25 | — | — | EP | disclosed |