SCHEMBL403893

SCHEMBL403893

C1=N[C](c2ccccc2)N=C1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NOTUM Q6P988 1/20 0.48
ALDH1A1 P00352 3/20 0.47
RAB9A P51151 5/20 0.43
NPC1 O15118 4/20 0.43
MAPK1 P28482 2/20 0.43
KMT2A Q03164 2/20 0.39
MEN1 O00255 1/20 0.39
SMN1; SMN2 Q16637 2/20 0.38
ATM Q13315 1/20 0.38
ALOX15 P16050 1/20 0.38
NFKB1 P19838 1/20 0.36
NFKB2 Q00653 1/20 0.36
RELA Q04206 1/20 0.36
CYP2E1 P05181 1/20 0.36
CYP2A6 P11509 1/20 0.36
CYP2B6 P20813 1/20 0.36
ATAD2 Q6PL18 1/20 0.36
CYP1A2 P05177 1/20 0.35
LMNA P02545 1/20 0.35
MAPT P10636 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1326009 0.73
Biphenyl SCHEMBL28890607 0.67 ALDH1A1 (1.00) NOTUMALDH1A1RAB9ANPC1MAPK1
SCHEMBL30108088 0.67 ALDH1A1 (1.00) NOTUMALDH1A1RAB9ANPC1MAPK1
SCHEMBL30629023 0.67 ALDH1A1 (1.00) NOTUMALDH1A1RAB9ANPC1MAPK1
Biphenyl SCHEMBL164 0.67 ALDH1A1 (1.00) NOTUMALDH1A1RAB9ANPC1MAPK1
SCHEMBL29560186 0.67 ALDH1A1 (1.00) NOTUMALDH1A1RAB9ANPC1MAPK1
Biphenyl SCHEMBL2548048 0.67 ALDH1A1 (1.00) NOTUMALDH1A1RAB9ANPC1MAPK1
Biphenyl SCHEMBL4002609 0.67 ALDH1A1 (1.00) NOTUMALDH1A1RAB9ANPC1MAPK1
Biphenyl SCHEMBL1358618 0.67 ALDH1A1 (1.00) NOTUMALDH1A1RAB9ANPC1MAPK1
Biphenyl SCHEMBL29008551 0.67 ALDH1A1 (1.00) NOTUMALDH1A1RAB9ANPC1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115335445-B Tackifier composition 花王株式会社 2024-05-03 CN disclosed
CN-115551966-A Adhesive composition 花王株式会社 2022-12-30 CN disclosed
CN-115335445-A Tackifier composition 花王株式会社 2022-11-11 CN disclosed
US-9425409-B2 Materials for electronic devices MERCK PATENT GMBH (DE) 2016-08-23 US disclosed
US-20130207048-A1 MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH PATENTS & SCIENTIFIC INFORMATION (DE) 2013-08-15 US disclosed
US-8361627-B2 Anti-corrosion layer for aluminum and magnesium alloys EADS DEUTSCHLAND GMBH (DE) 2013-01-29 US disclosed
US-20120021232-A1 ANTI-CORROSION LAYER FOR ALUMINUM AND MAGNESIUM ALLOYS TECHNISCHE UNIVERSITÄT WIEN (AT) 2012-01-26 US disclosed
EP-2379623-A1 ANTI-CORROSION LAYER FOR ALUMINUM AND MAGNESIUM ALLOYS EADS Deutschland GmbH (DE) 2011-10-26 EP disclosed
WO-2010081757-A1 ANTI-CORROSION LAYER FOR ALUMINUM AND MAGNESIUM ALLOYS EADS DEUTSCHLAND GMBH (DE) 2010-07-22 WO disclosed
EP-1221440-B1 Benzoheterocyclic derivatives useful as vasopressin or oxytocin modulators OTSUKA PHARMA CO LTD (JP) 2007-04-25 EP disclosed
US-5670526-A ANTIINFLAMMATORY AGENT, IMMUNOSUPPRESSANT OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1997-09-23 US disclosed
US-5656642-A Peripheral vasodilating agent containing piperidine derivative as active ingredient OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1997-08-12 US disclosed
EP-0765314-A1 BENZOHETEROCYCLIC DERIVATIVES USEFUL AS VASOPRESSIN OR OXYTOCIN MODULATORS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1997-04-02 EP disclosed
WO-1995034540-A1 BENZOHETEROCYCLIC DERIVATIVES USEFUL AS VASOPRESSIN OR OXYTOCIN MODULATORS OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) 1995-12-21 WO disclosed
US-5434164-A Carbostyril derivatives and salts thereof and pharmaceutical compositions for inhibiting adhesion of thrombocytes OTSUKA PHARMACEUTICAL CO. LTD. (JP) 1995-07-18 US disclosed
EP-0650476-A1 PERIPHERAL VASODILATING AGENT CONTAINING N-ACYLATED 4-AMINO PIPERIDINE DERIVATIVES AS ACTIVE INGREDIENTS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1995-05-03 EP disclosed
EP-0240015-B1 Carbostyril derivatives, process for preparing them, pharmaceutical composition, and use OTSUKA PHARMA CO LTD (JP) 1994-12-28 EP disclosed
WO-1994022826-A1 PERIPHERAL VASODILATING AGENT CONTAINING N-ACYLATED 4-AMINO PIPERIDINE DERIVATIVES AS ACTIVE INGREDIENTS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1994-10-13 WO disclosed
US-5008274-A Carbostyril derivatives and salts thereof and pharmaceutical composition for inhibiting adhesion of thrombocytes OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1991-04-16 US disclosed
EP-0240015-A2 Carbostyril derivatives, process for preparing them, pharmaceutical composition, and use OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1987-10-07 EP disclosed