Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4038533 | 0.72 | LCK (0.61) | LCK | |
| SCHEMBL4038945 | 0.69 | LCK (0.50) | LCK | |
| SCHEMBL4039642 | 0.67 | LCK (0.54) | LCKSRC | |
| SCHEMBL4038963 | 0.67 | LCK (0.56) | LCKSRC | |
| SCHEMBL4037406 | 0.66 | LCK (0.59) | LCK | |
| SCHEMBL4038739 | 0.66 | LCK (0.56) | LCKSRC | |
| SCHEMBL4041472 | 0.66 | LCK (0.70) | LCKSRC | |
| SCHEMBL4046022 | 0.66 | NOS1 (0.32) | — | |
| SCHEMBL7969896 | 0.66 | LCK (0.86) | LCKSRC | |
| SCHEMBL4036713 | 0.65 | LCK (0.55) | LCKSRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1066286-B1 | HETEROCYCLO-SUBSTITUTED IMIDAZOPYRAZINE PROTEIN TYROSINE KINASE INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2009-04-29 | — | — | EP | claimed |
| EP-1066286-B1 | HETEROCYCLO-SUBSTITUTED IMIDAZOPYRAZINE PROTEIN TYROSINE KINASE INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2009-04-29 | — | — | EP | disclosed |