Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | ABCG2 | Q9UNQ0 | 8/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | ECE1 | P42892 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4034526 | 0.97 | PPARG (0.47) | PPARGABCG2KDM4EALDH1A1HPGD | |
| SCHEMBL4034328 | 0.93 | PPARG (0.49) | PPARGABCG2KDM4EALDH1A1HPGD | |
| SCHEMBL4042000 | 0.86 | PPARG (0.51) | PPARGABCG2KDM4EALDH1A1HPGD | |
| SCHEMBL4034678 | 0.84 | PPARG (0.49) | PPARGABCG2KDM4EALDH1A1HPGD | |
| SCHEMBL4036191 | 0.84 | PPARG (0.49) | PPARGABCG2KDM4EALDH1A1HPGD | |
| SCHEMBL13648968 | 0.84 | PPARG (0.49) | PPARGABCG2KDM4EALDH1A1HPGD | |
| SCHEMBL3340894 | 0.81 | PPARG (0.50) | PPARGABCG2KDM4EALDH1A1HPGD | |
| SCHEMBL4035989 | 0.81 | PPARG (0.50) | PPARGABCG2KDM4EALDH1A1HPGD | |
| SCHEMBL4039498 | 0.81 | PPARG (0.50) | PPARGABCG2KDM4EALDH1A1HPGD | |
| SCHEMBL13654303 | 0.81 | ABCG2 (0.46) | ABCG2KDM4EALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7601754-B2 | Flavonoid compounds as therapeutic antioxidants | ANTOXIS LIMITED (GB) | 2009-10-13 | — | — | US | disclosed |
| EP-1534698-B1 | FLAVONOID COMPOUNDS AS THERAPEUTIC ANTIOXIDANTS | ROWETT RES INST (GB) | 2007-09-19 | — | — | EP | disclosed |
| US-20060137207-A1 | Flavonoid compounds as therapeutic antioxidants | ANTOXIS LIMITED (GB) | 2006-06-29 | — | — | US | disclosed |