Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 11/20 | 0.53 |
| ▸ | CTSS | P25774 | 3/20 | 0.42 |
| ▸ | CA1 | P00915 | 3/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.37 |
| ▸ | CA9 | Q16790 | 2/20 | 0.37 |
| ▸ | CCR1 | P32246 | 1/20 | 0.37 |
| ▸ | CTSV | O60911 | 2/20 | 0.36 |
| ▸ | CTSL | P07711 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4042980 | 0.94 | CTSK (0.53) | CTSKCTSSCA1CA2CA12 | |
| SCHEMBL4038667 | 0.93 | CTSK (0.54) | CTSKCTSSCA1CA2CCR1 | |
| SCHEMBL4042230 | 0.93 | CTSK (0.52) | CTSKCTSSCA1CA2CA12 | |
| SCHEMBL4040650 | 0.92 | CTSK (0.65) | CTSKCTSSCA1CA2CA12 | |
| SCHEMBL4039127 | 0.91 | CTSK (0.61) | CTSKCTSSCA1CA2CCR1 | |
| SCHEMBL4044649 | 0.91 | CTSK (0.65) | CTSKCTSSCA1CA2CA12 | |
| SCHEMBL4042967 | 0.91 | CTSK (0.52) | CTSKCTSSCA2CTSLPOLB | |
| SCHEMBL4045969 | 0.91 | CTSK (0.56) | CTSKCTSSCA1CA2CCR1 | |
| SCHEMBL4040991 | 0.91 | CTSK (0.52) | CTSKCTSSCA1CA2CCR1 | |
| SCHEMBL4044521 | 0.90 | CTSK (0.51) | CTSKCTSSCA1CA2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546150-B1 | PYRROLE DERIVATIVES AS INHIBITORS OF CYTEINE PROTEASES | AMURA THERAPEUTICS LTD (GB) | 2009-03-04 | — | — | EP | claimed |
| EP-1651592-B1 | NOVEL DIBENZO[B,F]OXEPINE-10-CARBOXAMIDES AND PHARMACEUTICAL USES THEREOF | NOVARTIS AG (CH) | 2009-04-29 | — | — | EP | disclosed |