Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 known ✓ | P08588 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.57 |
| ▸ | MAPT | P10636 | 7/20 | 0.57 |
| ▸ | RECQL | P46063 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | NPC1 | O15118 | 3/20 | 0.56 |
| ▸ | RAB9A | P51151 | 3/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | THRB | P10828 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL81881 | 0.98 | ADRB1 (0.61) | ADRB1ALDH1A1MAPTRECQLMEN1 | |
| SCHEMBL82441 | 0.98 | ADRB1 (0.61) | ADRB1ALDH1A1MAPTRECQLMEN1 | |
| SCHEMBL28567064 | 0.98 | ADRB1 (0.61) | ADRB1ALDH1A1MAPTRECQLMEN1 | |
| Lithium SCHEMBL31448685 | 0.95 | ADRB1 (0.59) | ADRB1ALDH1A1MAPTRECQLMEN1 | |
| SCHEMBL21065781 | 0.95 | ADRB1 (0.59) | ADRB1ALDH1A1MAPTRECQLMEN1 | |
| SCHEMBL327765 | 0.95 | ADRB1 (0.64) | ADRB1ALDH1A1MAPTRECQLMEN1 | |
| Hydrochloric Acid SCHEMBL16446845 | 0.93 | ADRB1 (0.61) | ADRB1ALDH1A1MAPTRECQLMEN1 | |
| SCHEMBL18118476 | 0.90 | ADRB1 (0.64) | ADRB1ALDH1A1MAPTRECQLMEN1 | |
| SCHEMBL18806576 | 0.86 | MAPT (0.50) | ADRB1ALDH1A1MAPTRECQLMEN1 | |
| SCHEMBL14866966 | 0.86 | MAPT (0.50) | ADRB1ALDH1A1MAPTRECQLMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1279519-B1 | Image forming material and ammonium compound | FUJIFILM CORP (JP) | 2009-07-01 | — | — | EP | disclosed |