Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30628067 | 0.78 | IDO1 (0.51) | IDO1 | |
| SCHEMBL29099152 | 0.78 | IDO1 (0.51) | IDO1 | |
| SCHEMBL30141307 | 0.77 | IDO1 (0.44) | IDO1 | |
| SCHEMBL123581 | 0.76 | IDO1 (0.54) | IDO1 | |
| SCHEMBL29376679 | 0.76 | IDO1 (0.54) | IDO1 | |
| SCHEMBL21236133 | 0.76 | IDO1 (0.52) | IDO1 | |
| SCHEMBL21236453 | 0.74 | IDO1 (0.51) | IDO1 | |
| SCHEMBL30100166 | 0.74 | IDO1 (0.51) | IDO1 | |
| SCHEMBL30628110 | 0.74 | IDO1 (0.53) | IDO1 | |
| SCHEMBL29099091 | 0.74 | IDO1 (0.53) | IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110139857-B | Sulfoximine, sulfoximinamide, sulfodiimine, and diimine sulfonamide compounds as indoleamine 2,3-dioxygenase inhibitors | 重庆复尚源创医药技术有限公司 | 2023-07-21 | — | — | CN | disclosed |
| US-8466275-B2 | Method for the preparation of 2-halo-2′-deoxyadenosine compounds from 2′-deoxyguanosine | BRIGHAM YOUNG UNIVERSITY (US) | 2013-06-18 | — | — | US | disclosed |
| EP-1556400-B1 | METHOD FOR THE PREPARATION OF 2-HALO-2 -DEOXYADENOSINE COMPOUNDS FROM 2 -DEOXYGUANOSINE | UNIV BRIGHAM YOUNG (US) | 2013-05-01 | — | — | EP | disclosed |
| US-20090270604-A1 | METHOD FOR THE PREPARATION OF 2-HALO-2'-DEOXYADENOSINE COMPOUNDS FROM 2'-DEOXYGUANOSINE | BRIGHAM YOUNG UNIVERSITY | 2009-10-29 | — | — | US | disclosed |
| US-7572909-B2 | Method for the preparation of 2-halo-2′-deoxyadenosine compounds from 2′-deoxyguanosine | BRIGHAM YOUNG UNIVERSITY (US) | 2009-08-11 | — | — | US | disclosed |
| EP-1879573-A4 | MODULATORS OF INDOLEAMINE 2,3-DIOXYGENASE AND METHODS OF USING THE SAME | INCYTE CORP (US) | 2009-07-08 | — | — | EP | disclosed |
| EP-1879573-A1 | MODULATORS OF INDOLEAMINE 2,3-DIOXYGENASE AND METHODS OF USING THE SAME | Incyte Corporation (US) | 2008-01-23 | — | — | EP | disclosed |
| US-20070032645-A1 | Method for the preparation of 2-halo-2'-deoxyadenosine compounds for 2'-deoxyguanosine | BRIGHAM YOUNG UNIVERSITY (US) | 2007-02-08 | — | — | US | disclosed |
| WO-2006122150-A1 | MODULATORS OF INDOLEAMINE 2,3-DIOXYGENASE AND METHODS OF USING THE SAME | INCYTE CORPORATION (US) | 2006-11-16 | — | — | WO | disclosed |
| EP-1556400-A2 | METHOD FOR THE PREPARATION OF 2-HALO-2 -DEOXYADENOSINE COMPOUNDS FROM 2 -DEOXYGUANOSINE | Brigham Young University (US) | 2005-07-27 | — | — | EP | disclosed |
| WO-2004028462-A2 | METHOD FOR THE PREPARATION OF 2-HALO-2'-DEOXYADENOSINE COMPOUNDS FROM 2'-DEOXYGUANOSINE | BRIGHAM YOUNG UNIVERSITY, TECHNOLOGY TRANSFER OFFICE (US) | 2004-04-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070032645-A1 | Method for the preparation of 2-halo-2'-deoxyadenosine compounds for 2'-deoxyguanosine | DCTD, CDA, UNG | IDO1 2511/4885 |
| US-20090270604-A1 | METHOD FOR THE PREPARATION OF 2-HALO-2'-DEOXYADENOSINE COMPOUNDS FROM 2'-DEOXYGUANOSINE | DCTD, CDA, UNG | IDO1 2446/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.