SCHEMBL403965

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL403388	0.91	S1PR1 (0.55)	TPH1S1PR1MEN1ALDH1A1KMT2A
	SCHEMBL402844	0.90	S1PR1 (0.51)	S1PR1MEN1ALDH1A1KMT2ATSHR
	SCHEMBL404790	0.89	TPH1 (0.50)	TPH1S1PR1MEN1ALDH1A1KMT2A
	SCHEMBL399856	0.89	S1PR1 (0.46)	TPH1S1PR1MEN1ALDH1A1KMT2A
	SCHEMBL403125	0.86	S1PR1 (0.50)	S1PR1SMN1; SMN2
	SCHEMBL2781745	0.86	S1PR1 (0.51)	S1PR1HSD17B10KDM4ENPC1SMN1; SMN2
	SCHEMBL404155	0.84	S1PR1 (0.46)	S1PR1MAPT
	SCHEMBL2778960	0.83	S1PR1 (0.63)	S1PR1
	SCHEMBL398412	0.83	S1PR1 (0.50)	S1PR1
	SCHEMBL401013	0.83	S1PR1 (0.48)	S1PR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.