SCHEMBL40399

SCHEMBL40399

O=Cc1cccc(Cl)c1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29672621 1.00
Ethane SCHEMBL2153770 0.95 CHRM5 (0.54)
Benzaldehyde SCHEMBL20557183 0.93 ALDH1A1 (0.61)
SCHEMBL28276590 0.91 HSD17B10 (0.67)
Dimethylamine SCHEMBL5202356 0.91 CHRM5 (0.50)
SCHEMBL18530648 0.91 CYP1A2 (0.53)
Ethylene Glycol SCHEMBL28617308 0.89 CYP1A2 (0.52)
SCHEMBL1443724 0.87 TRIM24 (0.53)
SCHEMBL10442284 0.86 ALDH1A1 (0.57)
SCHEMBL11873023 0.84 TDP1 (0.50)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 8107 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12624144-B2 Method for preparing hollow covalent organic framework materials ZHEJIANG UNIVERSITY (CN) 2026-05-12 US claimed
CN-121574130-A Synthesis method of pyrazolo [1,2-b ] phthalazine-5, 10-dione derivative as drug intermediate and catalytic system for synthesis 南京苏亦欣医药科技有限公司 2026-02-27 CN claimed
EP-4205741-B1 CYP2E1 INHIBITORS FOR THE TREATMENT OF INFLAMMATORY-MEDIATED DISEASES SUZHOU LINGXI BIOTECHNOLOGY CO LTD (CN) 2025-12-10 EP claimed
CN-119999682-A Bactericide for oilfield water treatment and preparation method thereof 滨州乾坤化工机械有限公司 2025-05-16 CN claimed
CN-116606265-B Protocatechu derivative and synthesis method and application thereof 山西大学 2025-05-02 CN claimed
US-20250136445-A1 HYDROGEN PEROXIDE MANUFACTURING PROCESS AND MANUFACTURING SYSTEM BASED ON PHOTOCHEMICAL REACTION KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2025-05-01 US claimed
CN-119899184-A Beta-carboline compound, preparation method thereof and application thereof in resisting Alzheimer disease 中国人民解放军北部战区总医院 2025-04-29 CN claimed
CN-119841727-A Method for directly preparing carboxylic ester compound from aromatic aldehyde, ketone and carboxylic acid 湖南第一师范学院 2025-04-18 CN claimed
CN-119775233-A Novel Schiff base of furoyl and synthetic method and application thereof 江西农业大学 2025-04-08 CN claimed
CN-119219504-B Method for synthesizing triarylmethane molecular skeleton by aromatic aldehyde and hydrazine hydrochloride substance 山东金科力电源科技有限公司 2025-03-14 CN claimed
US-4401594-A PROTEOLYTIC ENZYME INHIBIJTORS; CARDIOVASCULAR AND MUSCULAR DISORDERS NIPPON KAYAKU KABUSHIKI KAISHA (JP) 1983-08-30 US claimed
US-4358596-A Process for the preparation of 1,2,3-thiadiazol-5-yl ureas SCHERING AG (DE) 1982-11-09 US claimed
US-4304938-A Process for the preparation of 3-phenoxybenzenes CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA RT (HU) 1981-12-08 US claimed
US-4117006-A SOLVENT-FREE GAF CORPORATION (US) 1978-09-26 US claimed
US-4020059-A Process for preparing tertiary amines NIPPON SHOKUBAI KAGAKU KOGYO CO., LTD. (JA) 1977-04-26 US claimed
US-4018932-A 2,3,5,6-TETRAHYDRO-IMIDAZO (2,1-6) THIAZOLE AMERICAN CYANAMID COMPANY (US) 1977-04-19 US claimed
US-3975532-A ANALGESIC ICI UNITED STATES INC. (US) 1976-08-17 US claimed
US-3953596-A 8-Oxa-3-azabicyclo(3.2.1)octane analgesic compositions and method of alleviating pain in animals ICI UNITED STATES INC. (US) 1976-04-27 US claimed
US-3951964-A Method for preparing azines PRODUITS CHIMIQUES UGINE KUHLMANN (FR) 1976-04-20 US claimed
US-3951993-A HYPOTENSIVE, CORONARY VESSEL DILATORS BAYER AKTIENGESELLSCHAFT (DT) 1976-04-20 US claimed