Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 10/20 | 0.84 |
| ▸ | MAPT | P10636 | 2/20 | 0.68 |
| ▸ | LMNA | P02545 | 1/20 | 0.68 |
| ▸ | TP53 | P04637 | 1/20 | 0.68 |
| ▸ | THRB | P10828 | 1/20 | 0.68 |
| ▸ | HPGD | P15428 | 2/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | MMP13 | P45452 | 1/20 | 0.55 |
| ▸ | APEX1 | P27695 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2201315 | 0.88 | EGLN1 (1.00) | EGLN1MAPTLMNAHPGDKMT2A | |
| SCHEMBL7685030 | 0.85 | EGLN1 (0.74) | EGLN1MAPTLMNAHPGDALDH1A1 | |
| SCHEMBL4039311 | 0.85 | EGLN1 (0.74) | EGLN1LMNAKMT2AMEN1APEX1 | |
| SCHEMBL7690509 | 0.84 | EGLN1 (0.73) | EGLN1MAPTLMNATP53THRB | |
| SCHEMBL7690780 | 0.83 | EGLN1 (0.77) | EGLN1LMNAKMT2AALDH1A1MEN1 | |
| SCHEMBL2200760 | 0.82 | EGLN1 (1.00) | EGLN1MAPTALDH1A1 | |
| SCHEMBL4047637 | 0.82 | EGLN1 (0.83) | EGLN1MAPTKMT2AMEN1POLB | |
| SCHEMBL7690099 | 0.80 | EGLN1 (0.69) | EGLN1LMNAHPGDKMT2AMEN1 | |
| SCHEMBL923068 | 0.80 | HPGD (0.72) | MAPTLMNATP53THRBHPGD | |
| SCHEMBL617423 | 0.80 | KMT2A (0.62) | EGLN1MAPTLMNATP53THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2079699-A1 | QUINOLINE DERIVATIVES | Envivo Pharmaceuticals, Inc. (US) | 2009-07-22 | — | — | EP | claimed |
| WO-2008014602-A1 | QUINOLINE DERIVATIVES | ENVIVO PHARMACEUTICALS, INC. (US) | 2008-02-07 | — | — | WO | claimed |
| EP-2079699-A1 | QUINOLINE DERIVATIVES | Envivo Pharmaceuticals, Inc. (US) | 2009-07-22 | — | — | EP | disclosed |
| WO-2008014602-A1 | QUINOLINE DERIVATIVES | ENVIVO PHARMACEUTICALS, INC. (US) | 2008-02-07 | — | — | WO | disclosed |