Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 11/20 | 0.83 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.55 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2202554 | 0.87 | EGLN1 (0.80) | EGLN1MEN1KMT2AMAPTRAB9A | |
| Hydrochloric Acid SCHEMBL7689283 | 0.87 | EGLN1 (0.72) | EGLN1MEN1KMT2ANPC1 | |
| Hydrochloric Acid SCHEMBL7693361 | 0.86 | EGLN1 (0.79) | EGLN1MEN1KMT2AMAPTRAB9A | |
| SCHEMBL7961819 | 0.85 | EGLN1 (0.69) | EGLN1MEN1KMT2A | |
| SCHEMBL7687778 | 0.85 | EGLN1 (0.73) | EGLN1MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL4044392 | 0.84 | EGLN1 (0.72) | EGLN1POLBMEN1KMT2AMAPT | |
| Hydrochloric Acid SCHEMBL7689282 | 0.84 | EGLN1 (0.68) | EGLN1MEN1KMT2A | |
| SCHEMBL7964145 | 0.82 | EGLN1 (0.73) | EGLN1MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL7953380 | 0.82 | EGLN1 (0.73) | EGLN1GRM4MEN1KMT2AL3MBTL1 | |
| SCHEMBL8312850 | 0.82 | EGLN1 (0.73) | EGLN1MEN1KMT2ARAB9AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2079699-A1 | QUINOLINE DERIVATIVES | Envivo Pharmaceuticals, Inc. (US) | 2009-07-22 | — | — | EP | claimed |
| WO-2008014602-A1 | QUINOLINE DERIVATIVES | ENVIVO PHARMACEUTICALS, INC. (US) | 2008-02-07 | — | — | WO | claimed |
| EP-2079699-A1 | QUINOLINE DERIVATIVES | Envivo Pharmaceuticals, Inc. (US) | 2009-07-22 | — | — | EP | disclosed |
| WO-2008014602-A1 | QUINOLINE DERIVATIVES | ENVIVO PHARMACEUTICALS, INC. (US) | 2008-02-07 | — | — | WO | disclosed |