Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | ACACB | O00763 | 1/20 | 0.39 |
| ▸ | ACACA | Q13085 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | VEGFA | P15692 | 1/20 | 0.36 |
| ▸ | RARG | P13631 | 1/20 | 0.35 |
| ▸ | GCK | P35557 | 1/20 | 0.35 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4045199 | 0.88 | LMNA (0.58) | LMNAACACBACACALTA4HTSHR | |
| SCHEMBL4040995 | 0.86 | LMNA (0.57) | LMNAFFAR4MAOB | |
| SCHEMBL5718621 | 0.86 | LMNA (0.53) | LMNAFFAR4MAOBMAOA | |
| SCHEMBL4041294 | 0.85 | POLB (0.42) | LMNALTA4HTSHRNPC1MAPT | |
| SCHEMBL1835550 | 0.82 | LMNA (0.64) | LMNATSHRNPC1MAPTPOLB | |
| SCHEMBL6273026 | 0.82 | LMNA (0.64) | LMNATSHRNPC1MAPTPOLB | |
| SCHEMBL1840653 | 0.82 | LMNA (0.64) | LMNATSHRNPC1MAPTPOLB | |
| SCHEMBL4050938 | 0.80 | LMNA (0.53) | LMNAACACBACACALTA4HMAPT | |
| SCHEMBL5949941 | 0.80 | LMNA (0.78) | LMNATSHRMAPTPOLBNPSR1 | |
| SCHEMBL10452215 | 0.80 | MAP2K1 (0.38) | LMNAFFAR4TSHRNPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546150-B1 | PYRROLE DERIVATIVES AS INHIBITORS OF CYTEINE PROTEASES | AMURA THERAPEUTICS LTD (GB) | 2009-03-04 | — | — | EP | claimed |
| EP-1380342-B1 | COMPLEX CATALYST, PROCESS FOR PRODUCING THE COMPLEX CATALYST, AND PROCESS FOR PRODUCING ALCOHOL DERIVATIVE WITH THE COMPLEX CATALYST | SUMITOMO CHEMICAL CO (JP) | 2009-07-01 | — | — | EP | disclosed |
| US-6995110-B2 | Complex catalyst, process for producing the complex catalyst, and process for producing alcohol derivative with the complex catalyst | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2006-02-07 | — | — | US | disclosed |
| US-20040077487-A1 | Complex catalyst, process for producing the complex catalyst, and process for producing alchohol derivative with the complex catalyst | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2004-04-22 | — | — | US | disclosed |
| EP-1380342-A1 | COMPLEX CATALYST, PROCESS FOR PRODUCING THE COMPLEX CATALYST, AND PROCESS FOR PRODUCING ALCOHOL DERIVATIVE WITH THE COMPLEX CATALYST | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2004-01-14 | — | — | EP | disclosed |
| EP-0246713-B1 | INTERMEDIATES FOR THE PRODUCTION OF NITROGEN-CONTAINING SUBSTITUTED HETEROCYCLIC COMPOUNDS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1992-03-04 | — | — | EP | disclosed |
| US-4970222-A | INSECTICIDE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1990-11-13 | — | — | US | disclosed |
| US-4879292-A | Certain-phenoxy-phenoxy-alkylene-oxy-pyrimidines or symmetrical triazines, thio-analogues thereof, having insecticidal activity | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1989-11-07 | — | — | US | disclosed |
| EP-0128648-B1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUNDS, AND THEIR PRODUCTION AND USE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1988-08-17 | — | — | EP | disclosed |
| US-4751225-A | Certain 2-pyridyloxy-lower alkylene-oxy-phenoxy compounds, thio-and methylene analogues having insecticidal properties | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1988-06-14 | — | — | US | disclosed |
| EP-0246713-A2 | Intermediates for the production of nitrogen-containing substituted heterocyclic compounds | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1987-11-25 | — | — | EP | disclosed |
| EP-0128648-A1 | Nitrogen-containing heterocyclic compounds, and their production and use | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1984-12-19 | — | — | EP | disclosed |