SCHEMBL4040746

SCHEMBL4040746

Cc1ccc(Oc2cccc(OC(C)(C)C(=O)O)c2)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPARG P37231 11/20 0.55
PPARA Q07869 10/20 0.54
PPARD Q03181 6/20 0.54
CYP2C19 P33261 2/20 0.49
MEN1 O00255 1/20 0.49
CYP1A2 P05177 1/20 0.49
CYP3A4 P08684 1/20 0.49
CYP2D6 P10635 1/20 0.49
MAPT P10636 1/20 0.49
KMT2A Q03164 1/20 0.49
PTPN7 P35236 1/20 0.48
DUSP3 P51452 1/20 0.48
PTPN12 Q05209 1/20 0.48
PTPN22 Q9Y2R2 1/20 0.48
HTT P42858 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
FFAR4 Q5NUL3 1/20 0.46
FFAR1 O14842 1/20 0.45
CYP2C9 P11712 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4033102 0.87 PPARA (0.62) PPARGPPARAPPARDCYP2C19MEN1
SCHEMBL3483934 0.84 HTT (0.43) PPARGPPARAPPARDHTTTDP1
SCHEMBL4036545 0.83 PPARG (0.60) PPARGPPARAPPARDCYP2C19MEN1
SCHEMBL9911068 0.82 PPARG (0.55) PPARGPPARAPPARDCYP2C19MEN1
SCHEMBL22209208 0.82 PPARG (0.74) PPARGPPARAPPARDCYP2C19MEN1
SCHEMBL4033955 0.82 MAP4K4 (0.54) PPARGPPARAPPARDCYP2C19MEN1
SCHEMBL1045831 0.82 PPARA (0.69) PPARGPPARAPPARDCYP2C19MEN1
SCHEMBL11545612 0.80 PPARA (0.71) PPARGPPARAPPARDCYP2C19MEN1
SCHEMBL11399949 0.79 PPARG (0.57) PPARGPPARA
SCHEMBL7988206 0.79 PPARA (0.55) PPARGPPARAPPARDCYP2C19MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2049107-A2 SUBSTITUTED IMIDAZOLONE DERIVATIVES, PREPARATION AND USES Genfit (FR) 2009-04-22 EP disclosed
WO-2008012470-A2 SUBSTITUTED IMIDAZOLONE DERIVATIVES, PREPARATION AND USES GENFIT (FR) 2008-01-31 WO disclosed