Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 13/20 | 0.60 |
| ▸ | PPARA | Q07869 | 13/20 | 0.53 |
| ▸ | PPARD | Q03181 | 5/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.44 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.44 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.44 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4036404 | 0.89 | PPARG (0.66) | PPARGPPARAPPARDMEN1CYP1A2 | |
| SCHEMBL3484402 | 0.86 | PPARG (0.44) | PPARGPPARAPPARD | |
| SCHEMBL11738947 | 0.84 | PPARG (0.72) | PPARGPPARAPPARDMEN1CYP1A2 | |
| SCHEMBL4035509 | 0.84 | PPARG (0.57) | PPARGPPARAPPARD | |
| SCHEMBL4035971 | 0.84 | MAP4K4 (0.53) | PPARGPPARAPPARDMEN1MAPT | |
| SCHEMBL4040746 | 0.83 | PPARG (0.55) | PPARGPPARAPPARDMEN1CYP1A2 | |
| SCHEMBL4035957 | 0.81 | PPARG (0.48) | PPARGPPARAPPARDMEN1CYP1A2 | |
| SCHEMBL4033331 | 0.80 | PPARA (0.66) | PPARGPPARAPPARDMEN1CYP1A2 | |
| SCHEMBL4036197 | 0.80 | PPARG (0.66) | PPARGPPARAPPARDMEN1CYP1A2 | |
| SCHEMBL4040101 | 0.79 | PPARA (0.48) | PPARGPPARAPPARDCYP2C19PTPN7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2049107-A2 | SUBSTITUTED IMIDAZOLONE DERIVATIVES, PREPARATION AND USES | Genfit (FR) | 2009-04-22 | — | — | EP | disclosed |
| WO-2008012470-A2 | SUBSTITUTED IMIDAZOLONE DERIVATIVES, PREPARATION AND USES | GENFIT (FR) | 2008-01-31 | — | — | WO | disclosed |