Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 4/20 | 0.45 |
| ▸ | FLT1 | P17948 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KIT | P10721 | 4/20 | 0.41 |
| ▸ | ABL1 | P00519 | 2/20 | 0.41 |
| ▸ | CSF1R | P07333 | 2/20 | 0.41 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.41 |
| ▸ | FLT4 | P35916 | 2/20 | 0.41 |
| ▸ | IGF1R | P08069 | 1/20 | 0.41 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.41 |
| ▸ | TEK | Q02763 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6543856 | 0.87 | FLT1 (0.51) | KDRFLT1MAPTNPSR1TSHR | |
| SCHEMBL4041555 | 0.85 | F10 (0.45) | KDRFLT1KITABL1CSF1R | |
| SCHEMBL2229333 | 0.78 | KDR (0.67) | KDRFLT1KITABL1CSF1R | |
| SCHEMBL3864004 | 0.77 | F10 (0.48) | KDRFLT1NPC1RAB9AKIT | |
| SCHEMBL4041551 | 0.76 | F10 (0.47) | KDRFLT1KDM4EKITABL1 | |
| SCHEMBL4036769 | 0.75 | FLT1 (0.48) | KDRFLT1KITBRAFF10 | |
| SCHEMBL3106983 | 0.74 | KDR (0.46) | KDRMAPTNPC1RAB9APOLB | |
| SCHEMBL3863944 | 0.73 | FLT1 (0.52) | KDRFLT1KITABL1CSF1R | |
| SCHEMBL3869133 | 0.73 | KIT (0.59) | KDRFLT1KITABL1CSF1R | |
| SCHEMBL4035217 | 0.72 | HDAC3 (0.47) | KDRFLT1MAPTKITBRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1392680-B1 | SELECTIVE ANTHRANILAMIDE PYRIDINE AMIDES AS INHIBITORS OF VEGFR-2 AND VEGFR-3 | BAYER SCHERING PHARMA AG (DE) | 2009-07-22 | — | — | EP | disclosed |