Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5500987 | 0.84 | DPP4 (0.33) | HPGDDPP4 | |
| SCHEMBL25194097 | 0.83 | — | — | |
| SCHEMBL28818824 | 0.79 | CHRM2 (0.37) | HPGDDPP4 | |
| SCHEMBL22287170 | 0.78 | — | — | |
| SCHEMBL27533330 | 0.77 | MAPT (0.31) | — | |
| SCHEMBL26926785 | 0.76 | TACR1 (0.44) | — | |
| SCHEMBL11155986 | 0.76 | NEK2 (0.36) | NPC1RAB9AMEN1KMT2AHPGD | |
| SCHEMBL27993012 | 0.76 | NPC1 (0.31) | NPC1RAB9AMEN1KMT2AHPGD | |
| SCHEMBL605432 | 0.76 | TACR1 (0.37) | NPC1RAB9AMEN1KMT2AHPGD | |
| SCHEMBL28171027 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2051712-A2 | MODULATORS OF MUSCARINIC RECEPTORS | Vertex Pharmceuticals Incorporated (US) | 2009-04-29 | — | — | EP | disclosed |
| WO-2008021375-A2 | MODULATORS OF MUSCARINIC RECEPTORS | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2008-02-21 | — | — | WO | disclosed |