Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4042224 | 0.84 | NPC1 (0.33) | DPP4HPGD | |
| SCHEMBL5067770 | 0.80 | DPP4 (0.35) | DPP4POLBHPGDALOX5MAPT | |
| SCHEMBL6274182 | 0.79 | GNAI3 (0.41) | DPP4POLBHPGDALOX5MAPT | |
| SCHEMBL25194097 | 0.78 | — | — | |
| SCHEMBL28037367 | 0.78 | POLB (0.35) | DPP4POLBHPGDALOX5MAPT | |
| SCHEMBL3877432 | 0.78 | DPP4 (0.37) | DPP4POLBHPGDALOX5MAPT | |
| SCHEMBL21409408 | 0.78 | POLB (0.35) | DPP4POLBHPGDALOX5MAPT | |
| SCHEMBL5222630 | 0.76 | S1PR3 (0.40) | DPP4ALOX5 | |
| SCHEMBL28040142 | 0.75 | THRB (0.35) | DPP4POLBHPGDMAPT | |
| SCHEMBL7733041 | 0.74 | L3MBTL1 (0.43) | DPP4POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1761522-A1 | COMPOUNDS AND METHODS FOR TREATING DYSLIPIDEMIA | ELI LILLY AND COMPANY (US) | 2007-03-14 | — | — | EP | disclosed |
| WO-2006002342-A1 | COMPOUNDS AND METHODS FOR TREATING DYSLIPIDEMIA | ELI LILLY AND COMPANY (US) | 2006-01-05 | — | — | WO | disclosed |