Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | FABP5 | Q01469 | 3/20 | 0.39 |
| ▸ | FABP7 | O15540 | 2/20 | 0.39 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5941730 | 1.00 | KMT2A (0.40) | KMT2AFABP5FABP7PIN1EPHX2 | |
| Acetic Acid SCHEMBL5941723 | 0.87 | FABP5 (0.43) | KMT2AFABP5FABP7PIN1EPHX2 | |
| Acetic Acid SCHEMBL4042425 | 0.87 | FABP5 (0.43) | KMT2AFABP5FABP7PIN1EPHX2 | |
| SCHEMBL4040012 | 0.85 | FABP5 (0.45) | KMT2AFABP5FABP7EPHX2CA1 | |
| SCHEMBL16179303 | 0.77 | KMT2A (0.45) | KMT2AFABP5FABP7EPHX2OPRD1 | |
| SCHEMBL4050272 | 0.76 | FABP5 (0.47) | KMT2AFABP5FABP7EPHX2CA1 | |
| SCHEMBL3423135 | 0.76 | FABP5 (0.47) | KMT2AFABP5FABP7EPHX2CA1 | |
| SCHEMBL30686169 | 0.76 | FABP5 (0.47) | KMT2AFABP5FABP7EPHX2CA1 | |
| SCHEMBL30686135 | 0.76 | FABP5 (0.47) | KMT2AFABP5FABP7EPHX2CA1 | |
| SCHEMBL4448418 | 0.76 | FABP5 (0.47) | KMT2AFABP5FABP7EPHX2CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546150-B1 | PYRROLE DERIVATIVES AS INHIBITORS OF CYTEINE PROTEASES | AMURA THERAPEUTICS LTD (GB) | 2009-03-04 | — | — | EP | disclosed |
| CN-100354276-C | Biologically active compounds | AMURA THERAPEUTICS LTD (GB) | 2007-12-12 | — | — | CN | disclosed |
| CN-1681817-A | Biologically active compounds | AMURA THERAPEUTICS LTD (GB) | 2005-10-12 | — | — | CN | disclosed |
| EP-1546150-A1 | BIOLOGICALLY ACTIVE COMPOUNDS | Amura Therapeutics Limited (GB) | 2005-06-29 | — | — | EP | disclosed |
| WO-2004007501-A1 | BIOLOGICALLY ACTIVE COMPOUNDS | AMURA THERAPEUTICS LIMITED (GB) | 2004-01-22 | — | — | WO | disclosed |