SCHEMBL4042909

SCHEMBL4042909

C=CCCC(=CC(=C)C(=O)O)C(=O)O

nearest known ligand 0.48

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ABCC4 O15439 1/20 0.38
MAPT P10636 1/20 0.38
KDM4E B2RXH2 1/20 0.31
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2082248 0.83 KDM4E (0.48) ABCC4MAPTKDM4ETSHR
SCHEMBL4893568 0.78 LMNA (0.41) ABCC4MAPTKDM4ETSHR
SCHEMBL2747280 0.77 HDAC3 (0.39) KDM4ETSHR
SCHEMBL1561800 0.75 CAMK2A (0.41) KDM4ETSHR
SCHEMBL8997946 0.73 APEX1 (0.40) TSHR
SCHEMBL18169351 0.71 FFAR3 (0.35) KDM4ETSHR
SCHEMBL5595771 0.71 FFAR3 (0.35) KDM4ETSHR
SCHEMBL9860964 0.71 MAPT (0.47) ABCC4MAPTKDM4ETSHR
SCHEMBL28185977 0.71 ABCC4 (0.38) ABCC4MAPT
Acrylic Acid SCHEMBL4044076 0.71 LMNA (0.33) ABCC4MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2009103735-A1 COMPOSITION CONTAINING AN AMPHOLYTIC COPOLYMER ON THE BASIS OF QUATERNISED MONOMERS CONTAINING NITROGEN AND AT LEAST ONE POLYMER THAT DIFFERS FROM SAID COPOLYMER, AND USE THEREOF BASF SE (DE) 2009-08-27 WO disclosed