SCHEMBL4042911

SCHEMBL4042911

Cc1c(C)c(-c2ccc(C(C)C)cc2)c(C)c2c1OC1(CCN(C)CC1)C2c1ccc(C(C)C)cc1

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HPGD P15428 1/20 0.32
PTPN11 Q06124 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4042757 0.87 CYP1A2 (0.35) HPGD
SCHEMBL4039520 0.86 HPGD (0.32) HPGD
SCHEMBL4036102 0.83 HPGD (0.33) HPGD
SCHEMBL4821997 0.76
SCHEMBL2904763 0.76 F10 (0.36)
SCHEMBL2905550 0.76 CCR4 (0.35)
SCHEMBL2907932 0.75 HTR1F (0.37)
SCHEMBL3594071 0.74 HPGD (0.32) HPGD
SCHEMBL2908030 0.74 F10 (0.38)
SCHEMBL4821994 0.74 TACR1 (0.35) HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1323716-B1 PROMOTERS FOR THE PROLIFERATION AND DIFFERENTIATION OF STEM CELLS AND/OR NEURON PRECURSOR CELLS TAKEDA PHARMACEUTICAL (JP) 2009-01-14 EP claimed