Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 13/20 | 0.51 |
| ▸ | CTSS | P25774 | 5/20 | 0.38 |
| ▸ | CTSL | P07711 | 6/20 | 0.37 |
| ▸ | CTSB | P07858 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4042518 | 0.93 | CTSK (0.50) | CTSKCTSSCTSLCTSBMAPK1 | |
| SCHEMBL4047665 | 0.92 | CTSK (0.51) | CTSKCTSSCTSLCTSBMAPK1 | |
| SCHEMBL4041942 | 0.92 | CTSK (0.49) | CTSKCTSSCTSLCTSBMAPK1 | |
| SCHEMBL4048373 | 0.91 | CTSK (0.52) | CTSKCTSSCTSLCTSBMAPK1 | |
| SCHEMBL4048116 | 0.91 | CTSK (0.48) | CTSKCTSSCTSLCTSBMAPK1 | |
| SCHEMBL4046066 | 0.91 | CTSK (0.50) | CTSKCTSSCTSLCTSBMAPK1 | |
| SCHEMBL4048070 | 0.90 | CTSK (0.48) | CTSKCTSSCTSLCTSB | |
| SCHEMBL4053213 | 0.89 | CTSK (0.49) | CTSKCTSSCTSLCTSBMAPK1 | |
| SCHEMBL4046731 | 0.89 | CTSK (0.56) | CTSKCTSSCTSBDPP4 | |
| SCHEMBL4049584 | 0.89 | CTSK (0.51) | CTSKCTSSCTSLCTSBMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009103719-A1 | SUBSTITUTED 4-(INDOL-3-YL)QUINAZOLINES AND USE AND PRODUCTION THEREOF | FREIE UNIVERSITÄT BERLIN (DE) | 2009-08-27 | — | — | WO | disclosed |