Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 17/20 | 0.72 |
| ▸ | ABCG2 | Q9UNQ0 | 15/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4043595 | 0.91 | ABCB1 (0.59) | ABCB1ABCG2ALDH1A1NPSR1 | |
| SCHEMBL7171136 | 0.85 | ABCB1 (0.83) | ABCB1ABCG2 | |
| SCHEMBL4039110 | 0.84 | ABCB1 (0.68) | ABCB1ABCG2 | |
| SCHEMBL3885917 | 0.84 | ABCB1 (1.00) | ABCB1ABCG2 | |
| SCHEMBL7167675 | 0.82 | ABCB1 (0.90) | ABCB1ABCG2 | |
| SCHEMBL4040694 | 0.82 | ABCB1 (0.77) | ABCB1ABCG2 | |
| SCHEMBL7175058 | 0.81 | ABCB1 (0.76) | ABCB1ABCG2 | |
| SCHEMBL4038570 | 0.79 | ABCB1 (0.83) | ABCB1ABCG2 | |
| SCHEMBL4049215 | 0.77 | ABCB1 (0.75) | ABCB1ABCG2 | |
| SCHEMBL4043245 | 0.77 | SIGMAR1 (0.71) | ABCB1ABCG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934276-B1 | ANTHRANILIC ACID DERIVATIVES AS MULTI DRUG RESISTANCE MODULATORS | XENOVA LTD (GB) | 2003-12-17 | — | — | EP | claimed |
| US-6218393-B1 | IN THERAPY OF MULTIDRUG RESISTANT CANCERS, FOR EXAMPLE TO POTENTIATE CYTOTOXICITY OF CANCER DRUG | XENOVA LIMITED (GB) | 2001-04-17 | — | — | US | claimed |
| EP-1506188-B1 | PROCESS FOR THE PREPARATION OF A HYDRATE OF AN ANTHRANILIC ACID DERIVATIVE | XENOVA LTD (GB) | 2009-02-25 | — | — | EP | disclosed |