Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 7/20 | 0.63 |
| ▸ | CTSS | P25774 | 3/20 | 0.47 |
| ▸ | ACE | P12821 | 2/20 | 0.46 |
| ▸ | CCR1 | P32246 | 2/20 | 0.43 |
| ▸ | CTSV | O60911 | 2/20 | 0.41 |
| ▸ | CTSL | P07711 | 2/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.40 |
| ▸ | PREP | P48147 | 2/20 | 0.40 |
| ▸ | FAP | Q12884 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.39 |
| ▸ | PTAFR | P25105 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4042794 | 0.94 | CTSK (0.57) | CTSKCTSSACECCR1PREP | |
| SCHEMBL4042595 | 0.93 | CTSK (0.57) | CTSKCTSSACECCR1CTSL | |
| SCHEMBL4047037 | 0.93 | CTSK (0.56) | CTSKCTSSACECCR1PREP | |
| SCHEMBL4041333 | 0.92 | CTSK (0.69) | CTSKCTSSACEPREPFAP | |
| SCHEMBL4046945 | 0.92 | CTSK (0.55) | CTSKCTSSCHRNB2CHRNA7CHRNA4 | |
| SCHEMBL4039907 | 0.92 | CTSK (0.59) | CTSKCTSSACE | |
| SCHEMBL4046389 | 0.92 | CTSK (0.69) | CTSKCTSSACECCR1CHRNB2 | |
| SCHEMBL4040004 | 0.91 | CTSK (0.54) | CTSKCTSSACECCR1PREP | |
| SCHEMBL4043949 | 0.90 | CTSK (0.53) | CTSKCTSSACECHRNB2CHRNA7 | |
| SCHEMBL4042810 | 0.90 | CTSK (0.58) | CTSKCTSSCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546150-B1 | PYRROLE DERIVATIVES AS INHIBITORS OF CYTEINE PROTEASES | AMURA THERAPEUTICS LTD (GB) | 2009-03-04 | — | — | EP | claimed |