Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 6/20 | 0.41 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.41 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.41 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 2/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.34 |
| ▸ | SMYD3 | Q9H7B4 | 2/20 | 0.33 |
| ▸ | PEPD | P12955 | 1/20 | 0.32 |
| ▸ | XPNPEP1 | Q9NQW7 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4052363 | 0.88 | DPP4 (0.42) | DPP4DPP7DPP8DPP9CTSK | |
| SCHEMBL4043977 | 0.86 | DPP4 (0.44) | DPP4DPP7DPP8DPP9CTSK | |
| SCHEMBL4049054 | 0.84 | DPP4 (0.52) | DPP4DPP7DPP8DPP9CTSK | |
| SCHEMBL4044096 | 0.81 | DPP4 (0.45) | DPP4DPP7DPP8DPP9CTSK | |
| SCHEMBL4042196 | 0.81 | DPP4 (0.44) | DPP4DPP7DPP8DPP9CTSK | |
| SCHEMBL4052757 | 0.80 | DPP4 (0.48) | DPP4DPP7DPP8DPP9CTSK | |
| SCHEMBL4046908 | 0.80 | DPP4 (0.44) | DPP4DPP7DPP8DPP9CTSK | |
| SCHEMBL4045576 | 0.80 | DPP4 (0.44) | DPP4DPP7DPP8DPP9CTSK | |
| SCHEMBL4052226 | 0.80 | DPP4 (0.46) | DPP4DPP7DPP8DPP9CTSK | |
| SCHEMBL4037832 | 0.80 | CTSK (0.57) | CTSKSMYD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546150-B1 | PYRROLE DERIVATIVES AS INHIBITORS OF CYTEINE PROTEASES | AMURA THERAPEUTICS LTD (GB) | 2009-03-04 | — | — | EP | claimed |