Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | BLM | P54132 | 2/20 | 0.48 |
| ▸ | RECQL | P46063 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | F2 | P00734 | 1/20 | 0.48 |
| ▸ | F10 | P00742 | 1/20 | 0.48 |
| ▸ | F12 | P00748 | 1/20 | 0.48 |
| ▸ | F7 | P08709 | 1/20 | 0.48 |
| ▸ | F3 | P13726 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | PARP1 | P09874 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28201581 | 0.85 | ESR1 (0.38) | ESR1TSHRBLMRECQLHSD17B10 | |
| SCHEMBL7820108 | 0.78 | ESR1 (0.48) | ESR1TSHRBLMRECQLHSD17B10 | |
| SCHEMBL5084038 | 0.78 | ESR1 (0.48) | ESR1TSHRBLMRECQLHSD17B10 | |
| SCHEMBL11202321 | 0.78 | BLM (0.55) | ESR1TSHRBLMRECQLHSD17B10 | |
| SCHEMBL11202324 | 0.78 | BLM (0.55) | ESR1TSHRBLMRECQLHSD17B10 | |
| SCHEMBL9250790 | 0.78 | BLM (0.48) | ESR1TSHRBLMRECQLHSD17B10 | |
| SCHEMBL12262965 | 0.78 | BLM (0.48) | ESR1TSHRBLMRECQLHSD17B10 | |
| SCHEMBL5988427 | 0.77 | ESR1 (0.52) | ESR1TSHRHSD17B10POLBMAPT | |
| SCHEMBL28481713 | 0.77 | ESR1 (0.58) | ESR1TSHRTDP1ALDH1A1CES2 | |
| SCHEMBL1043886 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2079699-A1 | QUINOLINE DERIVATIVES | Envivo Pharmaceuticals, Inc. (US) | 2009-07-22 | — | — | EP | disclosed |
| WO-2008014602-A1 | QUINOLINE DERIVATIVES | ENVIVO PHARMACEUTICALS, INC. (US) | 2008-02-07 | — | — | WO | disclosed |
| WO-2007065524-A1 | ERYTHRULOSE ESTERS AS UV FILTERS | MERCK PATENT GMBH (DE) | 2007-06-14 | — | — | WO | disclosed |