Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4041610 | 0.85 | KCNH2 (0.54) | KCNH2 | |
| SCHEMBL13407409 | 0.84 | KCNH2 (0.44) | KCNH2 | |
| SCHEMBL3574972 | 0.84 | KCNH2 (0.44) | KCNH2 | |
| SCHEMBL14498845 | 0.77 | KCNH2 (0.63) | KCNH2 | |
| SCHEMBL13407405 | 0.76 | KCNH2 (0.49) | KCNH2 | |
| SCHEMBL14341180 | 0.74 | KCNH2 (0.53) | KCNH2 | |
| SCHEMBL5752097 | 0.74 | KCNH2 (0.51) | KCNH2 | |
| SCHEMBL14402346 | 0.74 | KCNH2 (0.41) | KCNH2 | |
| SCHEMBL3284629 | 0.74 | KCNH2 (0.41) | KCNH2 | |
| SCHEMBL3284637 | 0.74 | KCNH2 (0.41) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1537123-B1 | AMINO-SUBSTITUTED CYCLOHEXANE DERIVATIVES FOR THE TREATMENT OF BACTERIAL INFECTIONS | GLAXO GROUP LTD (GB) | 2009-04-29 | — | — | EP | claimed |