Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 19/20 | 0.54 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.48 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4044878 | 0.85 | KCNH2 (0.47) | KCNH2 | |
| SCHEMBL5261640 | 0.84 | KCNH2 (0.67) | KCNH2 | |
| SCHEMBL14498893 | 0.84 | KCNH2 (0.67) | KCNH2 | |
| SCHEMBL13407407 | 0.84 | KCNH2 (0.54) | KCNH2 | |
| SCHEMBL3582737 | 0.84 | KCNH2 (0.54) | KCNH2 | |
| SCHEMBL4507055 | 0.84 | KCNH2 (0.54) | KCNH2 | |
| SCHEMBL14524460 | 0.80 | KCNH2 (0.60) | KCNH2KCNQ1CACNA1C | |
| SCHEMBL14498851 | 0.77 | KCNH2 (0.69) | KCNH2 | |
| SCHEMBL5651296 | 0.76 | KCNH2 (0.56) | KCNH2 | |
| SCHEMBL5653812 | 0.76 | KCNH2 (0.56) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1537123-B1 | AMINO-SUBSTITUTED CYCLOHEXANE DERIVATIVES FOR THE TREATMENT OF BACTERIAL INFECTIONS | GLAXO GROUP LTD (GB) | 2009-04-29 | — | — | EP | claimed |