Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1E | P49674 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13964438 | 0.88 | CSNK1E (0.38) | CSNK1EHTR2AHTR2C | |
| Trifluoroacetic Acid SCHEMBL4042584 | 0.77 | CSNK1E (0.33) | CSNK1E | |
| SCHEMBL6631468 | 0.76 | CSNK1E (0.41) | CSNK1E | |
| SCHEMBL13964221 | 0.70 | HTR2A (0.36) | CSNK1EHTR2AHTR2C | |
| SCHEMBL4044886 | 0.69 | CSNK1E (0.36) | CSNK1E | |
| SCHEMBL14849195 | 0.58 | HTR2A (0.40) | CSNK1EHTR2AHTR2C | |
| SCHEMBL26136595 | 0.57 | CYP1A2 (0.35) | — | |
| SCHEMBL29229158 | 0.57 | CYP1A2 (0.35) | — | |
| SCHEMBL11426187 | 0.57 | CYP1A2 (0.35) | — | |
| Oxalic Acid SCHEMBL19877271 | 0.56 | P2RX7 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1436291-B1 | INDOLIZINES AS KINASE PROTEIN INHIBITORS | AVENTIS PHARMA SA (FR) | 2009-01-14 | — | — | EP | disclosed |