⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23114264 | 0.72 | MEN1 (0.43) | — | |
| SCHEMBL8098714 | 0.72 | NPC1 (0.35) | — | |
| SCHEMBL149636 | 0.72 | — | — | |
| SCHEMBL2495212 | 0.72 | — | — | |
| SCHEMBL4718559 | 0.69 | APP (0.58) | — | |
| SCHEMBL9593 | 0.67 | — | — | |
| SCHEMBL3712918 | 0.67 | — | — | |
| SCHEMBL904190 | 0.67 | KDM4E (0.37) | — | |
| SCHEMBL14656039 | 0.67 | — | — | |
| SCHEMBL9779757 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 568 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119350937-A | Double-component aerosol spray paint and preparation method thereof | 广东豪之盛新材料有限公司 | 2025-01-24 | — | — | CN | claimed |
| CN-102127081-B | Preparation method of adenine | WUHAN INST TECHNOLOGY | 2012-11-28 | — | — | CN | claimed |
| CN-102127081-A | Preparation method of adenine | WUHAN INST TECHNOLOGY | 2011-07-20 | — | — | CN | claimed |
| CN-101219997-B | Synthesis of 2-chlorine-5- amido pyrimidine | Suzhou bohong chemical technology co ltd | 2011-04-20 | — | — | CN | claimed |
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |
| CN-101219997-A | Synthesis of 2-chlorine-5- amido pyrimidine | SUZHOU YIELD PHARMACEUTICAL R (CN) | 2008-07-16 | — | — | CN | claimed |
| WO-2026041663-A1 | P2X7 RECEPTOR ANTAGONISTS | BREYE THERAPEUTICS APS (DK) | 2026-02-26 | — | — | WO | disclosed |
| EP-4699607-A2 | N-(HYDROXYALKYL (HETERO)ARYL) TETRAHYDROFURAN CARBOXAMIDES AS MODULATORS OF SODIUM CHANNELS | Vertex Pharmaceuticals Incorporated (US) | 2026-02-25 | — | — | EP | disclosed |
| EP-4695236-A1 | SUBSTITUTED PHENYL-PIPERAZINYL BASED MODULATORS FOR THE TREATMENT OF DISEASE | Soley Therapeutics, Inc. (US) | 2026-02-18 | — | — | EP | disclosed |
| EP-4334298-B1 | UREA DERIVATIVES WHICH CAN BE USED TO TREAT CANCER | SCORPION THERAPEUTICS INC (US) | 2026-02-18 | — | — | EP | disclosed |
| EP-4680612-A1 | CHEMICAL COMPOUNDS | AN2 Therapeutics, Inc. (US) | 2026-01-21 | — | — | EP | disclosed |
| US-12528827-B2 | Tricyclic heteroaryl-substituted quinoline and azaquinoline compounds as PAR4 inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2026-01-20 | — | — | US | disclosed |
| US-20250353836-A1 | N-(HYDROXYALKYL (HETERO)ARYL) TETRAHYDROFURAN CARBOXAMIDES AS MODULATORS OF SODIUM CHANNELS | VERTEX PHARMA (US) | 2025-11-20 | — | — | US | disclosed |
| EP-1483259-A1 | PYRIMIDINES AS NOVEL OPENERS OF POTASSIUM ION CHANNELS | Icagen, Inc. (US) | 2004-12-08 | — | — | EP | disclosed |
| CN-1501927-A | Trifluoromethylpurines as phosphodiesterase 4 inhibitors | 记忆药物公司 | 2004-06-02 | — | — | CN | disclosed |
| US-20030181465-A1 | Pyrimidines as novel openers of potassium ion channels | ICAGEN, INC. | 2003-09-25 | — | — | US | disclosed |
| WO-2003068767-A1 | PYRIMIDINES AS NOVEL OPENERS OF POTASSIUM ION CHANNELS | ICAGEN, INC. (US) | 2003-08-21 | — | — | WO | disclosed |
| CN-1226166-A | Formulations and methods for treating congestive heart failure | ELI LITTY AND COMPANY (US) | 1999-08-18 | — | — | CN | disclosed |
| CN-1194140-A | Medicine | LILLY CO ELI (US) | 1998-09-30 | — | — | CN | disclosed |
| CN-1145226-A | Method for treating substance abuse withdrawal | LILLY CO ELI (US) | 1997-03-19 | — | — | CN | disclosed |