SCHEMBL9593

SCHEMBL9593

Nc1ccc(Cl)nc1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL2840053 0.97
SCHEMBL4426627 0.87 PIK3CD (0.44)
SCHEMBL8174442 0.82 HSP90AA1 (0.59)
SCHEMBL4729780 0.80 PIK3CD (0.69)
SCHEMBL4434207 0.79 ALDH1A1 (0.52)
SCHEMBL21186393 0.75 MAOA (0.57)
SCHEMBL1662273 0.71 PIK3CD (0.73)
SCHEMBL17800 0.71
SCHEMBL1069905 0.71 CA12 (0.46)
SCHEMBL29374702 0.71 CA12 (0.46)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3091 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119613279-A N-substituted benzene ring bioisostere and preparation method thereof 上海交通大学 2025-03-14 CN claimed
CN-117924347-A Preparation method of monosulfur organosilane coupling agent 江西宏柏新材料股份有限公司 2024-04-26 CN claimed
CN-116675638-A Chemical synthesis method of 6-chloro-N-methylpyridine-3-amine 皖西学院 2023-09-01 CN claimed
CN-112898198-B Nitrogen-containing aromatic heterocyclic nitro compound and preparation method and application thereof 中国科学院长春应用化学研究所 2023-04-07 CN claimed
CN-113788859-B Large-steric-hindrance N-heterocyclic carbene-palladium complex, preparation method and application thereof, and synthetic method of sonchibu based on complex 中山大学 2023-03-31 CN claimed
WO-2022078306-A1 LARGE STERIC HINDERANCE PALLADIUM-NITROGEN-HETEROCYCLIC CARBENE COMPLEX, PREPARATION METHOD FOR SAME, APPLICATIONS OF SAME, AND SYNTHESIS METHOD FOR SONIDEGIB BASED ON SAME 中山大学 2022-04-21 WO claimed
CN-113788859-A Large-steric-hindrance N-heterocyclic carbene-palladium complex, preparation method and application thereof, and synthetic method of sonchibu based on complex 中山大学 2021-12-14 CN claimed
CN-112209972-A Large-steric-hindrance N-heterocyclic carbene-palladium complex, preparation method and application thereof, and synthetic method of sonchibu based on complex 中山大学 2021-01-12 CN claimed
CN-106045997-B The preparation method of 2- hydroxyl -1,5- naphthyridines 烟台凯博医药科技有限公司 2019-02-26 CN claimed
CN-106432069-A A method for preparation of 2-amino-5-chloro-pyridine 安徽工业大学 2017-02-22 CN claimed
WO-2002012442-A2 HETEROCYCLIC COMPOUNDS AS LIGANDS OF THE GABAA RECEPTOR NEUROGEN CORPORATION (US) 2002-02-14 WO claimed
JP-2002501024-A 2002-01-15 JP claimed
US-6176909-B1 IN POLYMERIC BINDER XEROX CORPORATION 2001-01-23 US claimed
EP-1051176-A1 SUBSTITUTED OXOAZAHETEROCYCLYL FACTOR Xa INHIBITORS Aventis Pharmaceuticals Products Inc. (US) 2000-11-15 EP claimed
WO-1999037304-A1 SUBSTITUTED OXOAZAHETEROCYCLYL FACTOR Xa INHIBITORS AVENTIS PHARMACEUTICALS PRODUCTS INC. (US) 1999-07-29 WO claimed
EP-0915843-A1 AZETIDINONE DERIVATIVES FOR THE TREATMENT OF ATHEROSCLEROSES SMITHKLINE BEECHAM PLC (GB) 1999-05-19 EP claimed
WO-1997041098-A1 AZETIDINONE DERIVATIVES FOR THE TREATMENT OF ATHEROSCLEROSIS SMITHKLINE BEECHAM PLC (GB) 1997-11-06 WO claimed
EP-0644881-B1 3-PYRIDAZINE DERIVATIVES AND THEIR USE IN RUBBER MONSANTO CO (US) 1997-07-30 EP claimed
EP-0726255-A2 3-Pyridazine derivatives and their use in rubber MONSANTO COMPANY (US) 1996-08-14 EP claimed
WO-1993025537-A1 3-PYRIDAZINE DERIVATIVES AND THEIR USE IN RUBBER MONSANTO COMPANY (US) 1993-12-23 WO claimed