SCHEMBL4045069

SCHEMBL4045069

CCNCCN(C)c1ccc2nc(Nc3c(C)cccc3C)c3cncn3c2n1

nearest known ligand 0.52

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
LCK P06239 19/20 0.52
SRC P12931 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4038238 0.94 LCK (0.58) LCKSRC
SCHEMBL4040544 0.91 LCK (0.50) LCKSRC
SCHEMBL4039642 0.88 LCK (0.54) LCKSRC
SCHEMBL4037062 0.85 LCK (0.57) LCKSRC
SCHEMBL4037055 0.83 LCK (0.59) LCKSRC
SCHEMBL4045072 0.82 LCK (0.54) LCKSRC
SCHEMBL4039029 0.82 LCK (0.59) LCKSRC
SCHEMBL4036713 0.81 LCK (0.55) LCKSRC
SCHEMBL4038784 0.81 LCK (0.51) LCKSRC
SCHEMBL4036352 0.81 LCK (0.51) LCKSRC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1066286-B1 HETEROCYCLO-SUBSTITUTED IMIDAZOPYRAZINE PROTEIN TYROSINE KINASE INHIBITORS BRISTOL MYERS SQUIBB CO (US) 2009-04-29 EP disclosed