Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.59 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.59 |
| ▸ | BAX | Q07812 | 1/20 | 0.59 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | ESR1 | P03372 | 2/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
| ▸ | MMP3 | P08254 | 1/20 | 0.46 |
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
| ▸ | MMP14 | P50281 | 1/20 | 0.46 |
| ▸ | MITF | O75030 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6289347 | 0.89 | ALDH1A1 (0.54) | LTA4HMEN1KMT2AKCNH2SCN3A | |
| SCHEMBL6290496 | 0.89 | ALDH1A1 (0.54) | LTA4HMEN1KMT2AKCNH2SCN3A | |
| SCHEMBL6289422 | 0.87 | SMN1; SMN2 (0.58) | LTA4HMEN1KMT2AKCNH2SCN3A | |
| SCHEMBL6293128 | 0.87 | SMN1; SMN2 (0.58) | LTA4HMEN1KMT2AKCNH2SCN3A | |
| SCHEMBL6290467 | 0.87 | SMN1; SMN2 (0.58) | LTA4HMEN1KMT2AKCNH2SCN3A | |
| SCHEMBL6290588 | 0.87 | SMN1; SMN2 (0.58) | LTA4HMEN1KMT2AKCNH2SCN3A | |
| SCHEMBL6290729 | 0.87 | SMN1; SMN2 (0.58) | LTA4HMEN1KMT2AKCNH2SCN3A | |
| SCHEMBL6290322 | 0.87 | SMN1; SMN2 (0.58) | LTA4HMEN1KMT2AKCNH2SCN3A | |
| SCHEMBL6293835 | 0.86 | ESR2 (0.57) | ESR2ESR1KCNH2SCN3AMMP2 | |
| SCHEMBL7940811 | 0.85 | ALDH1A1 (0.50) | MEN1KMT2AKCNH2SCN3AMMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10329270-B2 | Heteroaryl compounds as BTK inhibitors and uses thereof | MERCK PATENT GMBH (DE) | 2019-06-25 | — | — | US | disclosed |
| EP-3060550-B1 | HETEROARYL COMPOUNDS AS BTK INHIBITORS AND USES THEREOF | MERCK PATENT GMBH (DE) | 2019-05-15 | — | — | EP | disclosed |
| US-20160264548-A1 | HETEROARYL COMPOUNDS AS BTK INHIBITORS AND USES THEREOF | MERCK PATENT GMBH (DE) | 2016-09-15 | — | — | US | disclosed |
| EP-3060550-A2 | HETEROARYL COMPOUNDS AS BTK INHIBITORS AND USES THEREOF | Merck Patent GmbH (DE) | 2016-08-31 | — | — | EP | disclosed |
| WO-2015061247-A2 | HETEROARYL COMPOUNDS AS BTK INHIBITORS AND USES THEREOF | MERCK PATENT GMBH (DE) | 2015-04-30 | — | — | WO | disclosed |
| EP-1380342-B1 | COMPLEX CATALYST, PROCESS FOR PRODUCING THE COMPLEX CATALYST, AND PROCESS FOR PRODUCING ALCOHOL DERIVATIVE WITH THE COMPLEX CATALYST | SUMITOMO CHEMICAL CO (JP) | 2009-07-01 | — | — | EP | disclosed |
| CN-1281320-C | Complex catalyst process for producing the complex catalyst and process for producing alcohol derivative with the complex catalyst | SUMITOMO CHEMICAL CO (JP) | 2006-10-25 | — | — | CN | disclosed |
| US-6995110-B2 | Complex catalyst, process for producing the complex catalyst, and process for producing alcohol derivative with the complex catalyst | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2006-02-07 | — | — | US | disclosed |
| CN-1225456-C | Novel aromatic diamine and its polyimide | MITSUI CHEMICALS INC (JP) | 2005-11-02 | — | — | CN | disclosed |
| CN-1503696-A | Complex catalyst, process for producing the complex catalyst, and process for producing alcohol derivative using the complex catalyst | ס�ѻ�ѧ��ҵ��ʽ���� | 2004-06-09 | — | — | CN | disclosed |
| CN-1403438-A | Novel aromatic diamine and its polyimide | MITSUI CHEMICALS INC (JP) | 2003-03-19 | — | — | CN | disclosed |
| EP-0411676-B1 | Substituted dioxane derivatives | CIBA GEIGY AG (CH) | 1994-06-15 | — | — | EP | disclosed |
| EP-0411676-A1 | Substituted dioxane derivatives | CIBA-GEIGY AG (CH) | 1991-02-06 | — | — | EP | disclosed |
| US-4971981-A | PESTICIDES, INSECTICIDES, LARVICIDES | CIBA-GEIGY CORPORATION (US) | 1990-11-20 | — | — | US | disclosed |
| EP-0276196-A1 | Substituted dioxolane derivatives | CIBA-GEIGY AG (CH) | 1988-07-27 | — | — | EP | disclosed |
| US-4625048-A | PESTICIDES | HOFFMANN-LA ROCHE INC. (US) | 1986-11-25 | — | — | US | disclosed |
| EP-0072475-B1 | CARBAMIC ESTERS, PREPARATION THEREOF, PESTICIDAL COMPOSITIONS ON THE BASIS OF THESE COMPOUNDS AND THEIR USE IN COMBATING PESTS | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1986-08-20 | — | — | EP | disclosed |
| US-4607051-A | Carbamic acid compound and use as a pesticide | HOFFMANN-LA ROCHE INC. (US) | 1986-08-19 | — | — | US | disclosed |
| US-4413010-A | Carbamic acid esters and use as pesticides | HOFFMANN-LA ROCHE INC. (US) | 1983-11-01 | — | — | US | disclosed |
| EP-0072475-A2 | Carbamic esters, preparation thereof, pesticidal compositions on the basis of these compounds and their use in combating pests | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1983-02-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160264548-A1 | HETEROARYL COMPOUNDS AS BTK INHIBITORS AND USES THEREOF | BTK, SYK, LCK | LTA4H 1446/4885NR1H2 3917/4885BAX 1936/4885 |
| US-10329270-B2 | Heteroaryl compounds as BTK inhibitors and uses thereof | BTK, SYK, LCK | LTA4H 1446/4885NR1H2 3917/4885BAX 1936/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.