SCHEMBL40461

SCHEMBL40461

c1ccc(SOP(OSc2ccccc2)OSc2ccccc2)cc1

nearest known ligand 0.43

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.43
HPGD P15428 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
MGLL Q99685 1/20 0.43
HSD17B10 Q99714 1/20 0.43
ALDH1A1 P00352 1/20 0.38
MAPK1 P28482 1/20 0.38
FFAR1 O14842 1/20 0.31
LTA4H P09960 1/20 0.30
TSHR P16473 1/20 0.30
CYP3A4 P08684 1/20 0.30
TDP1 Q9NUW8 1/20 0.30
KCNH2 Q12809 1/20 0.30
MAOA P21397 1/20 0.30
MAOB P27338 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL887229 0.79 HPGD (0.39) MAPTHPGDSMN1; SMN2MGLLHSD17B10
SCHEMBL6692715 0.79 HPGD (0.39) MAPTHPGDSMN1; SMN2MGLLHSD17B10
SCHEMBL13271640 0.74
SCHEMBL141775 0.73 HPGD (0.50) MAPTHPGDSMN1; SMN2MGLLHSD17B10
SCHEMBL5672126 0.69 MAPT (0.45) MAPTHPGDSMN1; SMN2MGLLHSD17B10
SCHEMBL5695273 0.69
SCHEMBL5695276 0.69
SCHEMBL3092615 0.69
SCHEMBL8240702 0.69
SCHEMBL7182206 0.67 MAPT (0.43) MAPTHPGDSMN1; SMN2MGLLHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 109 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9200231-B2 Lubricating oil composition for rolling with round die IDEMITSU KOSAN CO., LTD. (JP) 2015-12-01 US claimed
US-20140296116-A1 LUBRICATING OIL COMPOSITION FOR ROLLING WITH ROUND DIE IDEMITSU KOSAN CO., LTD. (JP) 2014-10-02 US claimed
US-8835365-B2 Lubricating oil composition for rolling with round die IDEMITSU KOSAN CO., LTD. (JP) 2014-09-16 US claimed
US-6507049-B1 Encapsulants for solid state devices GENERAL ELECTRIC COMPANY 2003-01-14 US claimed
EP-0787791-B1 Functional fluid compositions having improved frictional and anti-oxidation properties LUBRIZOL CORP (US) 2002-12-18 EP claimed
WO-2002019440-A1 ENCAPSULANTS FOR SOLID STATE DEVICES GENERAL ELECTRIC COMPANY (US) 2002-03-07 WO claimed
EP-0787791-A2 Functional fluid compositions having improved frictional and anti-oxidation properties The Lubrizol Corporation (US) 1997-08-06 EP claimed
US-5561103-A CONTAINING SELF CONDENSATION PRODUCTS OF ALKYLTHIO ALKANOLS AND DISPERSANTS; LUBRICANTS THE LUBRIZOL CORPORATION (US) 1996-10-01 US claimed
US-5145889-A For light-emitting diodes KABUSHIKI KAISHA TOSHIBA (JP) 1992-09-08 US claimed
JP-56135548-A None JP disclosed
EP-4562707-A1 BATTERY THERMAL MANAGEMENT AND SAFETY METHOD AND DEVICE FOR IMPLEMENTING SAME TotalEnergies OneTech (FR) 2025-06-04 EP disclosed
EP-4551676-A1 USE OF AN ANTI-WEAR ADDITIVE FOR IMPROVING THE THERMAL CONDUCTIVITY OF A COOLING FLUID FOR AN ELECTRIC VEHICLE TotalEnergies OneTech (FR) 2025-05-14 EP disclosed
EP-4363537-A1 AQUEOUS LUBRICANT COMPOSITION FOR METALWORKING TotalEnergies OneTech (FR) 2024-05-08 EP disclosed
WO-2024022993-A1 BATTERY THERMAL MANAGEMENT AND SAFETY METHOD AND DEVICE FOR IMPLEMENTING SAME TOTALENERGIES ONETECH (FR) 2024-02-01 WO disclosed
EP-0028764-B1 POLYMERIC THERMO-SENSITIVE COMPOSITIONS MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1985-10-09 EP disclosed
US-4439569-A POLYAMIDE, BIS/HYDROXYPHENYL/SULFIDE, THIOPHOSPHITE MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1984-03-27 US disclosed
US-4303759-A REACTIVE SULFUR COMPOUND DECOMPOSES PEROXYL RADICAL AIR PRODUCTS AND CHEMICALS, INC. (US) 1981-12-01 US disclosed
JP-S56135548-A HIGH-MOLECULAR TEMPERATURE-SENSITIVE MATERIAL MATSUSHITA ELECTRIC IND CO LTD 1981-10-23 JP disclosed
EP-0028764-A1 Polymeric thermo-sensitive compositions MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1981-05-20 EP disclosed
US-4071423-A REACTION OF SECONDARY AMINE WITH CARBONYL SULFIDE AND UNSATURATED COMPOUND STAUFFER CHEMICAL COMPANY (US) 1978-01-31 US disclosed