SCHEMBL141775

SCHEMBL141775

c1ccc(SOSc2ccccc2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 2/20 0.50
MAPT P10636 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
MGLL Q99685 1/20 0.50
HSD17B10 Q99714 1/20 0.50
ALDH1A1 P00352 4/20 0.43
MAPK1 P28482 1/20 0.43
TSHR P16473 3/20 0.35
LTA4H P09960 1/20 0.35
FFAR1 O14842 1/20 0.35
MAOA P21397 2/20 0.33
MAOB P27338 2/20 0.33
KCNH2 Q12809 1/20 0.33
CA4 P22748 2/20 0.32
TDP1 Q9NUW8 2/20 0.31
ATM Q13315 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
ORAI1 Q96D31 1/20 0.30
ORAI2 Q96SN7 1/20 0.30
ORAI3 Q9BRQ5 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11143252 0.84 HPGD (0.38) HPGDMAPTSMN1; SMN2MGLLHSD17B10
SCHEMBL8763072 0.81 CA4 (0.54) HPGDSMN1; SMN2ALDH1A1LTA4HCA4
SCHEMBL11172087 0.79 MEN1 (0.52) MAPTMAOATDP1CA1CA2
SCHEMBL16690689 0.77 MAOA (0.38) HPGDMAPTSMN1; SMN2MGLLHSD17B10
SCHEMBL6268809 0.77 MAPT (0.31) HPGDMAPTSMN1; SMN2MGLLHSD17B10
SCHEMBL13271640 0.75
SCHEMBL3092615 0.75
SCHEMBL5672126 0.75 MAPT (0.45) HPGDMAPTSMN1; SMN2MGLLHSD17B10
SCHEMBL8240702 0.75
SCHEMBL5695276 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 4931 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4313996-B1 INDENONAPHTHOPYRANS HAVING TRIALKYLSILYL AND ETHYLENICALLY UNSATURATED GROUPS TRANSITIONS OPTICAL LTD (IE) 2026-05-06 EP claimed
EP-4049841-B1 HYBRID RESIN COMPOSITION CUBICURE GMBH (AT) 2026-03-18 EP claimed
EP-4034610-B1 DIHYDROQUINOLINE PHOTOCHROMIC COMPOUNDS TRANSITIONS OPTICAL LTD (IE) 2025-09-10 EP claimed
US-12404448-B2 Dihydroquinoline photochromic compounds TRANSITIONS OPTICAL, LTD. (IE) 2025-09-02 US claimed
CN-119371674-A Preparation method of donor-acceptor type metal organic framework photocatalyst and application of photocatalytic amine oxide/thioether 长沙理工大学 2025-01-28 CN claimed
CN-119264182-A Compound, preparation method thereof, resin material and application thereof 珠海莫界科技有限公司 2025-01-07 CN claimed
EP-4466319-A1 HIGH PERFORMANCE THERMOSET RESINS FOR 3D PRINTING Noga 3D Innovations Ltd (IL) 2024-11-27 EP claimed
US-20240376132-A1 Indenonaphthopyrans Having Trialkylsilyl and Ethylenically Unsaturated Groups TRANSITIONS OPTICAL, LTD. (IE) 2024-11-14 US claimed
US-20240219805-A1 GEL-CONTAINING ACTIVE FLUIDIC OPTICAL ELEMENT META PLATFORMS TECHNOLOGIES, LLC 2024-07-04 US claimed
US-20240198582-A1 HYBRID RESIN COMPOSITION FOR THE 3D-PRINTING OF OBJECTS CUBICURE GMBH (AT) 2024-06-20 US claimed
EP-0297995-A1 Polycyclic aromatic compounds, process for their preparation and their use in human and animal medicine and in cosmetics L'OREAL (FR) 1989-01-04 EP claimed
CN-85109096-B SYNTHELIZATION OF LINEAR MACROMOLECULAR POLYBENZEWNE THIOETHER 四川大学 1988-09-21 CN claimed
CN-85109096-A A kind of synthetic method of linear polyphenylthioether of high molecular weight 1987-06-24 CN claimed
CN-85102664-A A kind of synthetic method of linear polyphenylthioether of high molecular weight 1986-09-24 CN claimed
EP-0166935-A2 Substituted diphenyl ethers and diphenyl thioethers BAYER AG (DE) 1986-01-08 EP claimed
EP-0141612-A2 Curable Bisimide Resin Mixtures Technochemie GmbH - Verfahrenstechnik (DE) 1985-05-15 EP claimed
US-4482489-A USEFUL IN DIAZOTYPE SYSTEMS AND AS LATENT POLYMERIZATION INITIATORS JAMES RIVER GRAPHICS, INC. (US) 1984-11-13 US claimed
EP-0080108-A1 Diagnostic reagent and use thereof New York Blood Center, Inc. (US) 1983-06-01 EP claimed
US-4286964-A Polyfunctional epoxides and halohydrins used as bridging groups to bind aromatic amine group-containing alcohols and thiols to hydroxyl bearing substrates SEED BRIAN S 1981-09-01 US claimed
EP-0027377-A1 Derivatives of hydroxyl-bearing substrates, process for their preparation and a method of application Seed, Brian Sarsfield (US) 1981-04-22 EP claimed