Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATR | Q13535 | 19/20 | 0.79 |
| ▸ | EGFR | P00533 | 1/20 | 0.61 |
| ▸ | PRKDC | P78527 | 1/20 | 0.60 |
| ▸ | ATM | Q13315 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4041720 | 0.90 | ATR (0.82) | ATREGFRPRKDCATM | |
| SCHEMBL4039257 | 0.89 | ATR (0.80) | ATREGFRPRKDCATM | |
| SCHEMBL3057768 | 0.88 | ATR (1.00) | ATRPRKDCATM | |
| SCHEMBL4003249 | 0.83 | ATR (0.64) | ATREGFRPRKDCATM | |
| SCHEMBL4439513 | 0.79 | ATR (0.81) | ATREGFR | |
| SCHEMBL2387033 | 0.78 | ATR (0.71) | ATRPRKDCATM | |
| SCHEMBL3059386 | 0.78 | ATR (0.73) | ATRPRKDCATM | |
| SCHEMBL4006264 | 0.78 | ATR (0.69) | ATREGFRPRKDCATM | |
| SCHEMBL4045227 | 0.77 | ATR (0.68) | ATREGFR | |
| SCHEMBL2484717 | 0.77 | ATR (1.00) | ATREGFRPRKDCATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009024825-A1 | 2-PYRAZINYLBENZIMIDAZOLE DERIVATIVES AS RECEPTOR TYROSINE KINASE INHIBITORS | ASTRAZENECA AB (SE) | 2009-02-26 | — | — | WO | disclosed |