Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4039435 | 0.92 | PDE5A (0.58) | PDE5AKCNH2 | |
| SCHEMBL4036024 | 0.92 | PDE5A (0.68) | PDE5AKCNH2 | |
| SCHEMBL13810152 | 0.85 | PDE5A (0.66) | PDE5AKCNH2 | |
| SCHEMBL4039428 | 0.84 | PDE5A (0.66) | PDE5AKCNH2 | |
| SCHEMBL4039875 | 0.82 | PDE5A (0.74) | PDE5AKCNH2 | |
| SCHEMBL4041800 | 0.79 | PDE5A (0.56) | PDE5AKCNH2 | |
| SCHEMBL4036220 | 0.78 | PDE5A (0.79) | PDE5AKCNH2 | |
| SCHEMBL5247757 | 0.78 | PDE5A (0.73) | PDE5AKCNH2 | |
| SCHEMBL5247408 | 0.78 | PDE5A (0.81) | PDE5AKCNH2 | |
| SCHEMBL5248317 | 0.77 | PDE5A (0.81) | PDE5AKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1620437-B1 | 5,7-DIAMINOPYRAZOLO¬4,3-D PYRIMIDINES USEFUL IN THE TRAETMENT OF HYPERTENSION | PFIZER LTD (GB) | 2009-06-17 | — | — | EP | claimed |