Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4039868 | 0.91 | PDE5A (0.84) | PDE5AKCNH2 | |
| SCHEMBL4039435 | 0.89 | PDE5A (0.58) | PDE5AKCNH2 | |
| SCHEMBL4044735 | 0.88 | PDE5A (0.76) | PDE5AKCNH2 | |
| SCHEMBL8262377 | 0.87 | PDE5A (0.85) | PDE5AKCNH2 | |
| SCHEMBL8263385 | 0.85 | PDE5A (1.00) | PDE5AKCNH2 | |
| SCHEMBL4046910 | 0.82 | PDE5A (0.60) | PDE5AKCNH2 | |
| SCHEMBL4039428 | 0.81 | PDE5A (0.66) | PDE5AKCNH2 | |
| SCHEMBL5243728 | 0.79 | PDE5A (0.63) | PDE5AKCNH2 | |
| SCHEMBL331321 | 0.79 | PDE5A (0.59) | PDE5AKCNH2 | |
| SCHEMBL5426232 | 0.79 | PDE5A (0.69) | PDE5AKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1620437-B1 | 5,7-DIAMINOPYRAZOLO¬4,3-D PYRIMIDINES USEFUL IN THE TRAETMENT OF HYPERTENSION | PFIZER LTD (GB) | 2009-06-17 | — | — | EP | claimed |