Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.39 |
| ▸ | SELE | P16581 | 1/20 | 0.39 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | NCOA1 | Q15788 | 2/20 | 0.38 |
| ▸ | NCOA3 | Q9Y6Q9 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CDC25B | P30305 | 1/20 | 0.34 |
| ▸ | CYP17A1 | P05093 | 3/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 4/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | DAPK3 | O43293 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8448 | 0.71 | ICAM1 (0.45) | LMNAICAM1SELEVCAM1KDM4E | |
| SCHEMBL10970 | 0.70 | — | — | |
| SCHEMBL29865416 | 0.69 | KDM4E (0.56) | LMNAICAM1SELEVCAM1KDM4E | |
| SCHEMBL29865427 | 0.69 | KDM4E (0.56) | LMNAICAM1SELEVCAM1KDM4E | |
| Hydrochloric Acid SCHEMBL10879894 | 0.68 | CYP2A6 (0.40) | LMNAICAM1SELEVCAM1CYP17A1 | |
| Hydrochloric Acid SCHEMBL10877970 | 0.68 | CYP2A6 (0.40) | LMNAICAM1SELEVCAM1CYP17A1 | |
| SCHEMBL31509699 | 0.67 | ICAM1 (0.45) | LMNAICAM1SELEVCAM1KDM4E | |
| SCHEMBL7057856 | 0.67 | ICAM1 (0.45) | LMNAICAM1SELEVCAM1KDM4E | |
| SCHEMBL14438021 | 0.67 | ICAM1 (0.53) | LMNAICAM1SELEVCAM1KDM4E | |
| SCHEMBL5377179 | 0.67 | ICAM1 (0.45) | LMNAICAM1SELEVCAM1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2076512-A1 | FUSED THIAZOLE DERIVATIVES AS KINASE INHIBITORS | UCB Pharma S.A. (BE) | 2009-07-08 | — | — | EP | disclosed |
| WO-2008044022-A1 | FUSED THIAZOLE DERIVATIVES AS KINASE INHIBITORS | UCB PHARMA S.A. (BE) | 2008-04-17 | — | — | WO | disclosed |