⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10877970 | 0.98 | CYP2A6 (0.40) | — | |
| Hydrochloric Acid SCHEMBL10879894 | 0.98 | CYP2A6 (0.40) | — | |
| Isothiocyanate SCHEMBL28932932 | 0.88 | CYP2A6 (0.35) | — | |
| SCHEMBL27275151 | 0.82 | LMNA (0.38) | — | |
| SCHEMBL29788434 | 0.81 | — | — | |
| SCHEMBL88594 | 0.81 | — | — | |
| Isoquinoline SCHEMBL29082350 | 0.80 | NAMPT (0.38) | — | |
| Hydrochloric Acid SCHEMBL3872997 | 0.79 | CYP2A6 (0.40) | — | |
| SCHEMBL17350114 | 0.79 | CYP2A6 (0.40) | — | |
| SCHEMBL11068559 | 0.79 | CYP2A6 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2274 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250075265-A1 | ENHANCEMENT OF NUCLEIC ACID POLYMERIZATION BY AROMATIC COMPOUNDS | ROCHE SEQUENCING SOLUTIONS INC (US) | 2025-03-06 | — | — | US | claimed |
| CN-115103835-B | IL-17A modulators and uses thereof | 戴斯阿尔法公司 | 2024-12-10 | — | — | CN | claimed |
| US-11970731-B2 | Enhancement of nucleic acid polymerization by aromatic compounds | Roche Sequencing Solutions, Inc. (US) | 2024-04-30 | — | — | US | claimed |
| CN-116640152-A | Benzothiophene pyridine derivative and synthesis method thereof | 西安欧得光电材料有限公司 | 2023-08-25 | — | — | CN | claimed |
| EP-3735409-B1 | ENHANCEMENT OF NUCLEIC ACID POLYMERIZATION BY AROMATIC COMPOUNDS | STRATOS GENOMICS INC (US) | 2023-06-21 | — | — | EP | claimed |
| US-11547701-B2 | Compounds and compositions for the inhibition of NAMPT | VALO HEALTH, INC. (US) | 2023-01-10 | — | — | US | claimed |
| EP-3752492-B1 | FUNGICIDAL OXADIAZOLES | BAYER AG (DE) | 2022-12-21 | — | — | EP | claimed |
| CN-115103835-A | IL-17A modulators and uses thereof | 戴斯阿尔法公司 | 2022-09-23 | — | — | CN | claimed |
| EP-4031534-A1 | IL-17A MODULATORS AND USES THEREOF | Dice Alpha, Inc. (US) | 2022-07-27 | — | — | EP | claimed |
| EP-3999498-A1 | INHIBITORS OF CYCLIN-DEPENDENT KINASES | Kinnate Biopharma Inc. (US) | 2022-05-25 | — | — | EP | claimed |
| CN-1221407-A | Aminoisoquinolines and aminothienopyridine derivatives and their use as anti-inflammatory agents | ASTRA PHARMA PROD (GB) | 1999-06-30 | — | — | CN | claimed |
| EP-0892784-A1 | AMINOISOQUINOLINES AND AMINOTHIENOPYRIDINE DERIVATIVES AND THEIR USE AS ANTI-INFLAMMATORY AGENTS | Astra Pharmaceuticals Limited (GB) | 1999-01-27 | — | — | EP | claimed |
| WO-1997038977-A1 | AMINOISOQUINOLINES AND AMINOTHIENOPYRIDINE DERIVATIVES AND THEIR USE AS ANTI-INFLAMMATORY AGENTS | ASTRA PHARMACEUTICALS LTD. (GB) | 1997-10-23 | — | — | WO | claimed |
| EP-0236880-B1 | Penem derivatives | ERBA CARLO SPA (IT) | 1994-07-20 | — | — | EP | claimed |
| US-4886793-A | PENICILLINS; HUMANS OR ANIMALS | FARMITALIA CARLO ERBA, S.R.L. (IT) | 1989-12-12 | — | — | US | claimed |
| EP-0236880-A2 | Penem derivatives | FARMITALIA CARLO ERBA S.r.l. (IT) | 1987-09-16 | — | — | EP | claimed |
| US-4501739-A | BACTERICIDES, ANTIBIOTICS | ELI LILLY AND COMPANY (US) | 1985-02-26 | — | — | US | claimed |
| US-4496568-A | Antiinflammatory thieno [2,3-c]pyridine derivatives | PACOR (FR) | 1985-01-29 | — | — | US | claimed |
| US-4406898-A | ANTIBIOTICS CONTAINING A THIENOPYRIDINIUM OR FUROPYRIDINIUM GROUP | ELI LILLY AND COMPANY (US) | 1983-09-27 | — | — | US | claimed |
| US-3969358-A | Process for the preparation of thieno [3,2-c] pyridine and thieno [2,3-c] py | PARCOR (FR) | 1976-07-13 | — | — | US | claimed |