Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 14/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | SPR | P35270 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | NQO2 | P16083 | 1/20 | 0.31 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.31 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4047155 | 1.00 | REN (0.35) | RENKDM4EHPGDHSD17B10SPR | |
| SCHEMBL3772836 | 0.91 | REN (0.33) | RENKDM4EHPGDHSD17B10SPR | |
| SCHEMBL1051996 | 0.88 | KDM4E (0.36) | RENKDM4EHPGDHSD17B10SPR | |
| SCHEMBL3770013 | 0.87 | REN (0.36) | REN | |
| SCHEMBL4055979 | 0.86 | REN (0.32) | REN | |
| SCHEMBL4055983 | 0.86 | REN (0.32) | REN | |
| SCHEMBL4050700 | 0.85 | REN (0.33) | RENNQO2MTNR1AMTNR1B | |
| SCHEMBL4050697 | 0.85 | REN (0.33) | RENNQO2MTNR1AMTNR1B | |
| SCHEMBL4533875 | 0.85 | REN (0.32) | REN | |
| SCHEMBL4533870 | 0.85 | REN (0.32) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2061751-A1 | NITRATE ESTERS OF AMINOALCOHOLS | Novartis Ag (CH) | 2009-05-27 | — | — | EP | disclosed |
| WO-2008031811-A1 | NITRATE ESTERS OF AMINOALCOHOLS | SPEEDEL EXPERIMENTA AG (CH) | 2008-03-20 | — | — | WO | disclosed |