Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR5 | P35346 | 14/20 | 0.48 |
| ▸ | HRH1 | P35367 | 2/20 | 0.48 |
| ▸ | HTR2B | P41595 | 1/20 | 0.48 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | DCPS | Q96C86 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1748320 | 0.76 | SSTR5 (0.55) | SSTR5HRH1HTR2BSSTR1KCNH2 | |
| SCHEMBL1748554 | 0.72 | SSTR5 (0.47) | SSTR5HRH1HTR2BSSTR1KCNH2 | |
| SCHEMBL2955559 | 0.71 | SSTR5 (0.51) | SSTR5HRH1HTR2BSSTR1KCNH2 | |
| SCHEMBL1873520 | 0.71 | SSTR5 (0.51) | SSTR5HRH1HTR2BSSTR1KCNH2 | |
| SCHEMBL3782654 | 0.70 | SSTR5 (0.62) | SSTR5HRH1HTR2BSSTR1KCNH2 | |
| SCHEMBL3787442 | 0.70 | SSTR5 (0.67) | SSTR5HRH1HTR2BSSTR1KCNH2 | |
| SCHEMBL1748225 | 0.69 | SSTR5 (0.57) | SSTR5HRH1HTR2BSSTR1KCNH2 | |
| SCHEMBL3776629 | 0.69 | DCPS (0.61) | SSTR5HRH1HTR2BSSTR1KCNH2 | |
| SCHEMBL5558702 | 0.69 | SSTR5 (0.45) | SSTR5HRH1HTR2BSSTR1KCNH2 | |
| SCHEMBL3785769 | 0.68 | SSTR5 (0.65) | SSTR5HRH1HTR2BSSTR1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2001867-B1 | PYRIMIDINE, QUINAZOLINE, PTERIDINE AND TRIAZINE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2009-07-01 | — | — | EP | disclosed |